Generic ( Niacin )


Typical use Of Niacin :Hypercholesterolaemia, Hyperlipidemia, Hypertriglyceridaemia, Pellagra.
Mechanism of action of Niacin :Niacin Is A Derivative Of Vitamin B And Is Incorporated Into Coenzymes Nicotinamide Adenine Dinucleotide (NAD) And Nicotinamide Adenine Dinucleotide Phosphate (NADP), Which Are Involved In Multiple Cellular Metabolic Pathways. Niacin Also Reduces Total Serum Cholesterol, LDL, VLDL, And Triglycerides, And Increases HDL Cholesterol. It Appears To Decrease Hepatic Synthesis Of VLDL.
Drug Interaction of Niacin :Niacin Is Known To Interact With Other Drugs Like Alcohol, Atorvastatin, Colestipol (HCl), Fluvastatin, Glibornuride, Gliquidone, Technetium Tc-99m Disofenin, Technetium Tc-99m Lidofenin. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Niacin :Urticaria, Cramps, Myalgia, Blurred Vision, Acanthosis Nigricans, Ichthyosis, Toxic Amblyopia, Atrial Arrhythmias, Elevated Serum Aspartate Transaminase, Hepatitis, Hepatic Failure, Flushing, Headache, Pruritus, Diarrhea, Gastric Irritation, Flushing, Bloating.


INTERACTIONS OF NIACIN


How Niacin will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Niacin will impact during lactation(breastfeeding) ?

Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.

Medicine & Alcohol use and effect of Niacin

No Studies Found