Medicine : Nevirex (200mg)

Name:Nevirex (200mg)
Manufacturer:Aurobindo Pharma Ltd
Generic Use:Nevirapine
Composition:Nevirapine(200 Mg)
Substitutes:neviretro (200mg) , nevir (200mg) , nevimune (200mg) , nevivir (200mg) , neviraprine (200mg) , nevipan (200mg) , neve (200mg) , nevirex (200mg) , nev (200mg) , nevimune (60s)

Generic ( Nevirapine )

Typical use Of Nevirapine :In Combination With Other Antiretroviral Agents For The Treatment Of HIV-1 Infection.
Mechanism of action of Nevirapine :Nevirapine Binds Directly To Reverse Transcriptase (RT) And Blocks The RNA-dependent And DNA-dependent DNA Polymerase Activities By Causing A Disruption Of The Enzyme's Catalytic Site. The Activity Of Nevirapine Does Not Compete With Template Or Nucleoside Triphosphates.
Drug Interaction of Nevirapine :Rifampin (Rifadin), Rifabutin (Mycobutin),ketoconazole (Nizoral) And St. John's Wort Decrease Blood Concentrations Of Nevirapine By Increasing Its Breakdown. Decreased Blood Concentration May Reduce The Effect Of Nevirapine. Nevirapine Reduces The Blood Concentration Of Oral Contraceptives And This Could Result In Inadequate Birth Control. Nevirapine Also Decreases The Concentration Of Methadone (Dolophine) And This Could Lead To Narcotic Withdrawal Symptoms.
Side effects of Nevirapine :Hepatitis, Anaemia, Neuropsychiatric Reactions, Granulocytopenia (more Frequent In Children).


How Nevirapine will impact on Pregnancy ?

Experiences Of Drug Use And Evidence From Studies In Pregnant Women Have Shown Risk To Fetus. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Nevirapine will impact during lactation(breastfeeding) ?

Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.

Medicine & Alcohol use and effect of Nevirapine

No Studies Found