Medicine : Natrise Tab

Name:Natrise Tab
Type:Tablet
Manufacturer:Sun Pharmaceutical Industries Ltd
Generic Use:Tolvaptan
Composition:Tolvaptan(15 Mg)
Substitutes:tolvat (15tab) , natrise (15tab) , tolvasca (15mg) , hyponat o(30tab) , hyponat o(15tab 10) , natrise tab


Generic ( Tolvaptan )



Typical use Of Tolvaptan :Information Not Available.
Mechanism of action of Tolvaptan :Tolvaptan Is A Selective And Competitive Arginine Vasopressin Receptor 2 Antagonist. Vasopressin Acts On The V2 Receptors Found In The Walls Of The Vasculature And Luminal Membranes Of Renal Collecting Ducts. By Blocking V2 Receptors In The Renal Collecting Ducts, Aquaporins Do Not Insert Themselves Into The Walls Thus Preventing Water Absorption. This Action Ultimately Results In An Increase In Urine Volume, Decrease Urine Osmolality, And Increase Electrolyte-free Water Clearance To Reduce Intravascular Volume And An Increase Serum Sodium Levels.
Drug Interaction of Tolvaptan :Tolvaptan Is Known To Interact With Other Drugs Like Barbital, Bicalutamide, Carbamazepine, Conivaptan, Digoxin, Erythromycin, Fluconazole, Itraconazole, Ketoconazole, Phenytoin, Rifabutin, Ritonavir, Verapamil. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Tolvaptan :Asthenia, Constipation, Dry Mouth, Hyperglycemia, Pollakiuria, Polyuria, Thirst, Anorexia, Nausea.

INTERACTIONS OF TOLVAPTAN


How Tolvaptan will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Tolvaptan will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Tolvaptan

No Studies Found