Medicine : Narcotan (400mcg)

Name:Narcotan (400mcg)
Manufacturer:Troikaa Pharmaceuticals Ltd
Generic Use:Naloxone
Composition:Naloxone(400 Mcg)
Substitutes:nex (400mcg) , nalox (400mcg) , narcotan (400mcg) , nalox (1ml)

Generic ( Naloxone )

Typical use Of Naloxone :Cerebral Infarction, CNS Depression, Mental Illness, Overdosage With Opioids, Poisoning, Prophylaxis Of Stress Ulceration, Reversal Of Opioid-induced Respiratory Depression, Spinal Cord Trauma.
Mechanism of action of Naloxone :Naloxone Antagonizes The Opioid Effects By Competing For The Same Receptor Sites, Especially The Opioid Mu Receptor. Recently, Naloxone Has Been Shown To Bind All Three Opioid Receptors (mu, Kappa And Gamma) But The Strongest Binding Is To The Mu Receptor.
Drug Interaction of Naloxone :Naloxone (HCl) Is Known To Interact With Other Drugs Like Alcohol, Buprenorphine (HCl), Clonidine (HCl), Dextromoramide (Tartrate), Dihydrocodeine (Tartrate), Dipipanone (HCl), Enflurane, Levorphanol, Nalbuphine (HCl), Oxymorphone, Pentazocine. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Naloxone :Hypertension, Ventricular Fibrillation, Pulmonary Edema, Ventricular Arrhythmias, Nausea And Vomiting.


How Naloxone will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Naloxone will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Naloxone

No Studies Found