Medicine : Metadrate (200ml)

Name:Metadrate (200ml)
Type:Syrup
Manufacturer:Lupin Laboratories Ltd
Generic Use:Magaldrate , Metoclopramide
Composition:Magaldrate(480MG) , Metoclopramide(10mg)
Substitutes:metadrate (200ml) , metadrate (200ml)


Generic ( Magaldrate )



Typical use Of Magaldrate :Acid Peptic Disorders.Reflux Oesophagitis.
Mechanism of action of Magaldrate :Magaldrate Is A Hydroxymagnesium Aluminate Complex That Is Rapidly Converted In Gastric Acid To Magnesium And Aluminium Hydroxide, Which Is Poorly Absorbed And Provides A Sustained Antacid Effect With Balanced Efects On Intestinal Motility, Increases Lower Esophageal Sphincter Tone And Inhibits Smooth Muscle Contraction And Gastric Emptying.
Drug Interaction of Magaldrate :Megaldrate Is Known To Interact With Other Drugs Like Tetracycline, Iron Salts, Chlorpromazine, Levodopa, Isoniazid, Digoxin, H2-antagonists, Indomethacin, Nitrofurantoin, And Dicumarol. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Magaldrate :Nausea, Vomiting, Rashes, Muscular Weakness, Hives, Diarrhea, Constipation, Intestinal Pain.

INTERACTIONS OF MAGALDRATE


How Magaldrate will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Magaldrate will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Magaldrate

No Studies Found






Generic ( Metoclopramide )



Typical use Of Metoclopramide :Nausea And Vomiting, Gastritis, Gastrooesophageal Reflux, Heart Burn. Hiccups. Pre/post Operative Nausea, Vomiting. Lactation Failure.
Mechanism of action of Metoclopramide :Metoclopramide Inhibits Gastric Smooth Muscle Relaxation Produced By Dopamine, Therefore Increasing Cholinergic Response Of The Gastrointestinal Smooth Muscle. It Accelerates Intestinal Transit And Gastric Emptying By Preventing Relaxation Of Gastric Body And Increasing The Phasic Activity Of Antrum. Simultaneously, This Action Is Accompanied By Relaxation Of The Upper Small Intestine, Resulting In An Improved Coordination Between The Body And Antrum Of The Stomach And The Upper Small Intestine.
Drug Interaction of Metoclopramide :Metoclopramide (HCl) Is Known To Interact With Other Drugs Like Aspirin, Atovaquone, Atropine (Sulphate), Barium Sulphate, Benorylate, Biperiden (HCl), Bromocriptine (Mesylate), Cabergoline, Chlordiazepoxide (HCl), Chlorothiazide, Chlorpromazine (HCl), Chlorprothixene, Choline Magnesium Trisalicylate, Cimetidine (HCl), Clozapine, Cyclosporin A, Digitoxin, Digoxin, Droperidol. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Metoclopramide :Parkinsonism, Acute Dystonia, Acute Porphyria, Acute Dyskinesia, Tachycardia, Drowsiness, Drowsiness, Diarrhea, Akathisia, Impotence, Hypotension, Gynecomastia, Galactorrhea, Hypertension, Increase In Heart Rate, Hyperprolactinemia.

INTERACTIONS OF METOCLOPRAMIDE


How Metoclopramide will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Metoclopramide will impact during lactation(breastfeeding) ?

Possibly Unsafe: Evidence From Studies In Breastfeeding Women Show That There Is A Definite Risk Of Side Effects To The Breastfed Infants. However, Use Of The Drug In Breastfeeding Women Is Acceptable In Spite Of The Risk To The Infants, If The Drug Is Needed In A Life-threatening Situation Or For A Serious Disease For Which Safer Drugs Cannot Be Used Or Are Ineffective. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Metoclopramide

No Studies Found