Generic ( Memantine )


Typical use Of Memantine :Induction And Maintenance Of Anaesthesia.
Mechanism of action of Memantine :Memantine Binds More Effectively Than Mg2+ Ions At The NMDA Receptor, And Thereby Effectively Blocks This Prolonged Influx Of Ca2+ Ions Through The NMDA Channel Whilst Preserving The Transient Physiological Activation Of The Channels By Higher Concentrations Of Synaptically Released Glutamate. Thus Memantine Protects Against Chronically Elevated Concentrations Of Glutamate. Glutamate May Contribute To The Pathogenesis Of Alzheimer's Disease By Overstimulating Various Glutamate Receptors Resulting In Excitotoxicity And Neuronal Cell Death.
Drug Interaction of Memantine :Memantine Is Known To Interact With Other Drugs Like Apomorphine, Pergolide. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Memantine :Dizziness, Tiredness, Headache, Vomiting, Anxiety, Confusion, Hallucination, Cystitis, Hypertonia.


INTERACTIONS OF MEMANTINE


How Memantine will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Memantine will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Memantine

No Studies Found