Generic ( Melatonin )


Typical use Of Melatonin :Disturbed Biorhythms, Sleep Disorders.
Mechanism of action of Melatonin :Melatonin Is A Derivative Of Tryptophan. It Binds To Melatonin Receptor Type 1A, Which Then Acts On Adenylate Cylcase And The Inhibition Of A CAMP Signal Transduction Pathway. Melatonin Not Only Inhibits Adenylate Cyclase, But It Also Activates Phosphilpase C. This Potentiates The Release Of Arachidonate. By Binding To Melatonin Receptors 1 And 2, The Downstream Signallling Cascades Have Various Effects In The Body. The Plasma Levels Of Melatonin Are High At Night And Low During The Day And It Appears To Have A Role In Circardian Rhythm Regulation. This Action Of Melotonin Finds A Possible Place In The Management Of Jet Lag And Other Sleep Disorders. Melatonin Is Also Being Used In The Treatment Of Cluster Headaches.
Drug Interaction of Melatonin :Melatonin Is Known To Interact With Other Drugs Like Nifedipine. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Melatonin :Increased Seizure Activity, Drowsiness, Headache, Disruption Of Normal Circadian Rhythm.


INTERACTIONS OF MELATONIN


How Melatonin will impact on Pregnancy ?

There Are No Studies Available Regarding Its Use During Pregnancy. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Melatonin will impact during lactation(breastfeeding) ?

There Are No Studies Available Regarding Its Use During Lactation. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Melatonin

No Studies Found