Medicine : Megaclox Dt

Name:Megaclox Dt
Type:Tablet
Manufacturer:Cipla Ltd
Generic Use:Ampicillin , Cloxacillin
Composition:Ampicillin(125mg) , Cloxacillin(5mg)
Substitutes:megaclox dt , megaclox dt


Generic ( Ampicillin )



Typical use Of Ampicillin :Gram Positve Bacteria, H-influenzae, E-coli, Proteus, Salmonella And Shigella, Strep.viridans, Pneumococci, Gonococci And Meningococci.Urinary Tract Infections. Respiratory Tract Infections. Meningitis. Gonorrhoea. Cholecystitis. Subacute Bacterial Endocarditis. Septicaemias And Mixed Infections.
Mechanism of action of Ampicillin :By Binding To Specific Penicillin-binding Proteins (PBPs) Located Inside The Bacterial Cell Wall, Ampicillin Inhibits The Third And Last Stage Of Bacterial Cell Wall Synthesis. Cell Lysis Is Then Mediated By Bacterial Cell Wall Autolytic Enzymes Such As Autolysins; It Is Possible That Ampicillin Interferes With An Autolysin Inhibitor.
Drug Interaction of Ampicillin :Simultaneous Use With Oral Contraceptives May Lead To Increased Risk Of Breakthrough Bleeding And Reduced Efficacy Of The Contraceptive. Skin Rash Increased With Allopurinol. Probenecid Increases Blood Levels.
Side effects of Ampicillin :Urticaria, Eosinophilia, Leucopenia, Neutropenia, Seizures, Agranulocytosis, Hemolysis, Dizziness, Headache, Anorexia, Diarrhea, Abdominal Pain, Maculopapular Rash, Gastritis, Elevation Of Liver Enzymes.

INTERACTIONS OF AMPICILLIN


How Ampicillin will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Ampicillin will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Ampicillin

No Studies Found






Generic ( Cloxacillin )



Typical use Of Cloxacillin :Bacterial Infections, Bone And Joint Infection, Cystitis, Endocarditis, Enterocolitis, Meningitis Associated With Spina Bifida, Respiratory Tract Infections, Septicaemia.
Mechanism of action of Cloxacillin :By Binding To Specific Penicillin-binding Proteins (PBPs) Located Inside The Bacterial Cell Wall, Cloxacillin Inhibits The Third And Last Stage Of Bacterial Cell Wall Synthesis. Cell Lysis Is Then Mediated By Bacterial Cell Wall Autolytic Enzymes Such As Autolysins; It Is Possible That Cloxacillin Interferes With An Autolysin Inhibitor.
Drug Interaction of Cloxacillin :Cloxacillin Is Known To Interact With Other Drugs Like Chloramphenicol, Probenecid, Tetracycline (HCl). These Interactions Are Sometimes Beneficial And Sometimes May Pose Threats To Life. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Cloxacillin :Cholestatic Jaundice, Hemolytic Anemia, Blood Dyscrasias, Seizures, Interstitial Nephritis, Vomiting, Diarrhea, GI Disturbances, Skin Reactions, Rashes, Phlebitis, Glossitis, Stomatitis.

INTERACTIONS OF CLOXACILLIN


How Cloxacillin will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Cloxacillin will impact during lactation(breastfeeding) ?

Safer: Drug Has Been Studied In Few Breastfeeding Women And The Evidence Shows That There Is No Increase In Side Effects In The Infants, Or The Possibility Of Harm To The Breastfed Infants Is Expected To Be Rare. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Cloxacillin

No Studies Found