Medicine : Mefetrac Kit

Name:Mefetrac Kit
Manufacturer:Fourrts India Laboratories Pvt Ltd
Generic Use:Mifepristone , Misoprostol
Composition:Mifepristone(200 Mg) , Misoprostol(250 Mg)
Substitutes:mefetrac kit , mefetrac kit

Generic ( Mifepristone )

Typical use Of Mifepristone :Abortion, Contraception, Hypothyroid Coma, Induction Of Labour, Menstruation Disorders, Muscle Spasm Of Varied Aeitology, Routine Management Of The 3rd Stage Of Labour, Severe Nausea And Vomiting (prevention), Softening And Dilatation Of Cervix Before Mechanical Cervical Dilatation.
Mechanism of action of Mifepristone :The Anti-progestational Activity Of Mifepristone Results From Competitive Interaction With Progesterone At Progesterone-receptor Sites. The Compound Inhibits The Activity Of Endogenous Or Exogenous Progesterone. The Termination Of Pregnancy Results. Mifepristone Blocks The Binding Of Cortisol To Its Receptor. It Does Not Decrease Cortisol Production But Reduces The Effects Of Excess Cortisol, Such As High Blood Sugar Levels.
Drug Interaction of Mifepristone :Mifepristone Is Known To Interact With Other Drugs Like Aspirin, Ergometrine (Maleate), Gemeprost, Tenoxicam. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Mifepristone :Heavy Bleeding.


How Mifepristone will impact on Pregnancy ?

The Drug Should Not Be Used By Pregnant Women. Experiences Of Drug Use And Evidence From Studies In Pregnant Women Have Shown High Risk To Fetus. The Risk Of Drug Use In Pregnant Women Outweighs The Benefit.

How Mifepristone will impact during lactation(breastfeeding) ?

Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.

Medicine & Alcohol use and effect of Mifepristone

No Studies Found

Generic ( Misoprostol )

Typical use Of Misoprostol :Termination Of Pregnancy (49 Days Or Less Duration).Cervical Ripening Before Surgical Termination Of Pregnancy In The 1st Trimester.Prevention And Treatment Of NSAID Associated Gastrointestinal Injury And Blood Loss.Benign Gastric And Duodenal Ulcer (not Usually Recommended).
Mechanism of action of Misoprostol :Misoprostol, A Synthetic Prostaglandin E1 Analogue, Exerts Its Antisecretory Activity By Directly Acting On Specific Prostaglandin Receptors Found On The Surface Of Gastric Parietal Cells. It Exerts Its Protective Effects On The Mucosa By Replacing The Prostaglandins Consumed During Prostaglandin-inhibiting Therapies E.g. NSAIDs.
Drug Interaction of Misoprostol :Tell Your Doctor Of All Prescription And Nonprescription Medication You May Use. Do Not Start Or Stop Any Medicine Without Doctor Or Pharmacist Approval.
Side effects of Misoprostol :Nausea, Stomach Upset, Skin Rash, Acute Toxicity.


How Misoprostol will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Misoprostol will impact during lactation(breastfeeding) ?

Possibly Unsafe: Evidence From Studies In Breastfeeding Women Show That There Is A Definite Risk Of Side Effects To The Breastfed Infants. However, Use Of The Drug In Breastfeeding Women Is Acceptable In Spite Of The Risk To The Infants, If The Drug Is Needed In A Life-threatening Situation Or For A Serious Disease For Which Safer Drugs Cannot Be Used Or Are Ineffective. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Misoprostol

No Studies Found