Medicine : Maximin Drop(15ml)

Name:Maximin Drop(15ml)
Type:Drop
Manufacturer:Anglo-french Drugs & Industries Ltd
Generic Use:Cholecalciferol , Riboflavin Sodium Phosphate , Thiamine Hydrochloride , Tocopherol Acetate , Vitamin A
Composition:Cholecalciferol(200 Iu) , Riboflavin Sodium Phosphate(1.5 Mg) , Thiamine Hydrochloride(NULL) , Tocopherol Acetate(2.5 IU) , Vitamin A(2500 Iu)
Substitutes:maximin drop(15ml) , maximin drop(15ml) , maximin drop(15ml) , maximin drop(15ml) , maximin drop(15ml)


Generic ( Cholecalciferol )



Typical use Of Cholecalciferol :To Prevent And Treat Vitamin D Deficiency In Adults And Teenagers, And Vitamin D Dependent Rickets. It Can Be Used With Other Medicines To Treat Bone Disorder (osteoporosis), Low Levels Of Calcium Or Phosphate Caused By Certain Disorders (hypoparathyroidism, Pseudohypoparathyroidism, Familial Hypophosphatemia). It May Also Be Used In Kidney Disease To Keep Calcium Levels Normal And Allow Normal Bone Growth. Cholecalciferol Drops Are Given To Breast-fed Infants As A Supplement.
Mechanism of action of Cholecalciferol :Cholecalciferol Is Important For The Absorption Of Calcium From The Stomach And For The Functioning Of Calcium In The Body. It Regulates The Blood Levels Of Calcium And Phosphorus And Also Plays Key Role In The Absorption Of Calcium In Bone Tissue.
Drug Interaction of Cholecalciferol :Taking Cholecalciferol With Thiazide Diuretics (hydrochlorothiazide) Increases The Risk Of High Levels Of Blood Calcium. Cholecalciferol If Taken Along With Systemic Corticosteroids May Reduce Calcium Absorption. Cholecalciferol May Also Interact With Cholestyramine, Rifampicin, Phenytoin Or Barbiturates, Laxatives Which Contain Paraffin Oil, Glucocorticoids, And Cardiac Glycosides (digoxin). Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Cholecalciferol :Urge To Vomit (nausea), Vomiting Constipation, Loss Of Appetite, Increased Thirst, Increased Urination, Mental/mood Changes, Unusual Tiredness, Stomach Upset, Skin Rash, Serious Allergic Reactions Such As Swollen Face, Lips, Tongue Or Throat, Difficulty In Swallowing, Red Bumpy Itchy Skin, Difficulty In Breathing, Increased Levels Of Blood Calcium, And Increased Levels Of Urine Calcium.

INTERACTIONS OF CHOLECALCIFEROL


How Cholecalciferol will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Cholecalciferol will impact during lactation(breastfeeding) ?

Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.

Medicine & Alcohol use and effect of Cholecalciferol

No Studies Found






Generic ( Riboflavin Sodium Phosphate )



Typical use Of Riboflavin Sodium Phosphate :Arabinoflavinosis, Vitamin Deficiency.
Mechanism of action of Riboflavin Sodium Phosphate :Binds To Riboflavin Hydrogenase, Riboflavin Kinase, And Riboflavin Synthase. Riboflavin Is The Precursor Of Flavin Mononucleotide (FMN, Riboflavin Monophosphate) And Flavin Adenine Dinucleotide (FAD). The Antioxidant Activity Of Riboflavin Is Principally Derived From Its Role As A Precursor Of FAD And The Role Of This Cofactor In The Production Of The Antioxidant Reduced Glutathione. Reduced Glutathione Is The Cofactor Of The Selenium-containing Glutathione Peroxidases Among Other Things. The Glutathione Peroxidases Are Major Antioxidant Enzymes. Reduced Glutathione Is Generated By The FAD-containing Enzyme Glutathione Reductase.
Drug Interaction of Riboflavin Sodium Phosphate :Arabinoflavinosis, Vitamin Deficiency.
Side effects of Riboflavin Sodium Phosphate :Discoloration Of Urine, Swelling Of Face, Difficulty Breathing, Swelling Of Lips And Tongue.

INTERACTIONS OF RIBOFLAVIN SODIUM PHOSPHATE


How Riboflavin Sodium Phosphate will impact on Pregnancy ?

There Is Sufficient Evidence To Suggest That There Is No Risk To The Fetus In The First Trimester (12 Weeks) Of Pregnancy And There Is No Evidence Of Risk In Later Trimesters. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Riboflavin Sodium Phosphate will impact during lactation(breastfeeding) ?

Safer: Drug Has Been Studied In Few Breastfeeding Women And The Evidence Shows That There Is No Increase In Side Effects In The Infants, Or The Possibility Of Harm To The Breastfed Infants Is Expected To Be Rare. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Riboflavin Sodium Phosphate

No Studies Found






Generic ( Thiamine Hydrochloride )



Typical use Of Thiamine Hydrochloride :Lung Cancer And Pancreatic Cancer, Mild Chronic Deficiency, Severe Deficiency, Thiamine Deficiency Prophylaxis, Thiamine Deficiency Treatment.
Mechanism of action of Thiamine Hydrochloride :Thiamine Is Mainly The Transport Form Of The Vitamin, While The Active Forms Are Phosphorylated Thiamine Derivatives. There Are Five Known Natural Thiamine Phosphate Derivatives: Thiamine Monophosphate (ThMP), Thiamine Diphosphate (ThDP), Also Sometimes Called Thiamine Pyrophosphate (TPP), Thiamine Triphosphate (ThTP), And The Recently Discovered Adenosine Thiamine Triphosphate (AThTP), And Adenosine Thiamine Diphosphate. Each Derivative Has Unique Functions, However, Most Are Involved As Coenzymes.
Drug Interaction of Thiamine Hydrochloride :Thiamine Is Known To Interact With Other Drugs Like Aluminium Hydroxide And Oxide, Amiloride (HCl), Bumetanide, Chlorthalidone, Estradiol (Valerate), Estrogens Conjugated, Fluorouracil, Magnesium Carbonate, Magnesium Oxides And Hydroxides, Metformin (HCl), Phenobarbital Sodium, Phenobarbitone, Triamterene, Vecuronium (Br). Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Thiamine Hydrochloride :Nausea, Urticaria, Gi Bleeding, Angioneurotic Edema, Restlessness, Pruritis, Pulmonary Edema, Hemorrhage, Cyanosis,

INTERACTIONS OF THIAMINE HYDROCHLORIDE


How Thiamine Hydrochloride will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Thiamine Hydrochloride will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Thiamine Hydrochloride

No Studies Found






Generic ( Tocopherol Acetate )



Typical use Of Tocopherol Acetate :Cardiovascular Disease, Dementia, Haemolytic Anaemia, Hepatotoxin Poisoning, Metal Poisoning, Vitamin Deficiency, Malignant Neoplasms, Muscular Spasm, Parkinsonism, Prophylaxis And Treatment Of Angina, Retinopathy, Surgery.
Mechanism of action of Tocopherol Acetate :Vitamin E's Anti-atherogenic Activity Involves The Inhibition Of The Oxidation Of LDL And The Accumulation Of OxLDL In The Arterial Wall. It Also Appears To Reduce OxLDL-induced Apoptosis In Human Endothelial Cells. Vitamin E Inhibits Protein Kinase C (PKC) Activity. The Inhibition Of PKC Results In Inhibition Of Smooth Muscle Cell Proliferation, Which Is Involved In Atherogenesis.Vitamin E's Antithrombotic And Anticoagulant Activities Involves The Downregulation Of The Expression Of Intracellular Cell Adhesion Molecule(ICAM)-1 And Vascular Cell Adhesion Molecule(VCAM)-1 Which Lowers The Adhesion Of Blood Components To The Endothelium. Vitamin E Upregulates The Expression Of Cytosolic Phospholipase A2 And Cyclooxygenase (COX)-1 Which In Turn Enhances The Release Of Prostacyclin. Prostacyclin Is A Vasodilating Factor And Inhibitor Of Platelet Aggregation And Platelet Release. Vitamin E Has Also Been Found In Culture To Decrease Plasma Production Of Thrombin, A Protein Which Binds To Platelets And Induces Aggregation. A Metabolite Of Vitamin E Called Vitamin E Quinone Or Alpha-tocopheryl Quinone (TQ) Is A Potent Anticoagulant. This Metabolite Inhibits Vitamin K-dependent Carboxylase, Which Is A Major Enzyme In The Coagulation Cascade. Many Disorders Of The Nervous System Are Caused By Oxidative Stress. Vitamin E Protects Against This Stress, Thereby Protecting The Nervouse System.
Drug Interaction of Tocopherol Acetate :Tocopherol (Vitamin E) Is Known To Interact With Other Drugs Like Colestipol (HCl), Desogestrel, Retinol (Vitamin A), Vitamin K, Warfarin (Na). Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Tocopherol Acetate :Thrombosis, Bleeding In Vitamin K Deficient Patients, Necrotizing Enterocolitis In Premature Infants, Flatulence, Weakness, Dizziness, Fatigue, Nausea, Diarrhea, Abdominal Pain, Blurred Vision, Thrombophlebitis, Myopathy, Hypertension.

INTERACTIONS OF TOCOPHEROL ACETATE


How Tocopherol Acetate will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Tocopherol Acetate will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Tocopherol Acetate

No Studies Found






Generic ( Vitamin A )



Typical use Of Vitamin A :Vitamin A Is A Fat Soluble Vitamin And Is Effective For The Treatment Of Vitamin A Deficiency And Abnormal Dryness Of The Conjunctiva And Cornea Of The Eye, With Swelling And Ridge Formation.
Mechanism of action of Vitamin A :Vitamin A Is Required For Proper Growth And Development, Good Eye Sight, And To Increase The Immunity Of The Body. In Eye, It Helps In The Formation Of Retina Which Is Required For Both Low-light And Color Vision. Vitamin A As Retinoic Acid Is A Growth Factor For Epithelial And Other Cells.
Drug Interaction of Vitamin A :Vitamin A Is Known To Interact Significantly With Other Drugs Birth Control Pills, Blood Thinners (warfarin), Synthetic Vitamin A Preparations, And Cholestyramine. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Vitamin A :Severe Allergic Reactions, Inflammation Of Skin Of Face, Conjunctival Inflammation, Dry Mucus, Inflammation Of Skin Adjacent To Nails, Haziness Of Cornea, Peeling Of Skin Of Palms And Feet, Ulcers And Inflammation Of Corners Of Lips, And Hair Fall.

INTERACTIONS OF VITAMIN A


How Vitamin A will impact on Pregnancy ?

There Are No Studies Available Regarding Its Use During Pregnancy. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Vitamin A will impact during lactation(breastfeeding) ?

There Are No Studies Available Regarding Its Use During Lactation. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Vitamin A

No Studies Found