Medicine : Masai Tab

Name:Masai Tab
Type:Tablet
Manufacturer:Flamingo Pharmaceuticals Ltd
Generic Use:Aceclofenac , Drotaverine
Composition:Aceclofenac(100mg) , Drotaverine(80mg)
Substitutes:drolgan , masai tab , drolgan , masai tab


Generic ( Aceclofenac )


Typical use Of Aceclofenac :Aceclofenac Is Used To Relieve Pain And Inflammation Of Joints And Vertebrae In Conditions Such As Osteoarthritis, Rheumatoid Arthritis And Ankylosing Spondylitis.
Mechanism of action of Aceclofenac :Aceclofenac Works By Blocking The Effect Of Chemicals Called Cyclooxygenase Enzymes. These Enzymes Help To Make Other Chemicals In The Body, Called Prostaglandins. Prostaglandins Are Produced At Sites Of Injury Or Damage, And Cause Pain And Swelling. By Blocking The Effect Of Cyclooxygenase Enzymes, Production Of Prostaglandins Are Reduced, Thus, Pain And Swelling Are Eased. 
Drug Interaction of Aceclofenac :Aceclofenac May Increase Concentrations Of Lithium, Digoxin And Methotrexate In The Blood, Increase The Activity Of Anticoagulants (warfarin), Reduce The Activity Of Diuretics (furosemide) And Anti-hypertensives, Cause Increased Toxicity In Kidney (cyclosporine). Interaction With Quinolone Antibiotics (ciprofloxacin, Levofloxacin), Anti-diabetic Drugs, Pain Killers (aspirin, Ibuprofen), Or Corticosteroids Can Cause Adverse Effects. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Aceclofenac :The Most Common Side Effects Are Gastrointestinal In Nature Including Ulcers In The Mouth, Stomach And Small Intestine, Urge To Vomit, Vomiting, Diarrhea, Constipation, Excessive Passage Of Wing Or Gas, Indigestion, Abdominal Pain, Blood In Stools. Other Common Side Effects Are Swelling Of Part Or Whole Of The Body, Increased Blood Pressure, Heart Failure, And Severe Allergic Reactions.

INTERACTIONS OF ACECLOFENAC

How Aceclofenac will impact on Pregnancy ?

Experiences Of Drug Use And Evidence From Studies In Pregnant Women Have Shown Risk To Fetus. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Aceclofenac will impact during lactation(breastfeeding) ?

Possibly Unsafe: Evidence From Studies In Breastfeeding Women Show That There Is A Definite Risk Of Side Effects To The Breastfed Infants. However, Use Of The Drug In Breastfeeding Women Is Acceptable In Spite Of The Risk To The Infants, If The Drug Is Needed In A Life-threatening Situation Or For A Serious Disease For Which Safer Drugs Cannot Be Used Or Are Ineffective. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Aceclofenac

No Studies Found





Generic ( Drotaverine )


Typical use Of Drotaverine :Cholangitis, Cholecystitis, Cholecytolithiasis, Cystitis, Nephrolithiasis, Papilitis, Smooth Muscle Spasm, Stone Formation, Ureterolithiasis, Urolithiasis, Vesical Tenesmus.
Mechanism of action of Drotaverine :Drotaverine Inhibits Phosphodiesterases Hydrolysing CAMP, Thereby Increasing CAMP Concentration, Decreasing Ca Uptake Of The Cells And Changing The Distribution Of Calcium Among The Cells. It May Also Have Minor Allosteric Calcium Channel Blocking Properties.
Drug Interaction of Drotaverine :Not Known
Side effects of Drotaverine :Dizziness, Headache, Nausea, Palpitation, Constipation, Insomnia, Hypotension.

INTERACTIONS OF DROTAVERINE

How Drotaverine will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Drotaverine will impact during lactation(breastfeeding) ?

Safer: Drug Has Been Studied In Few Breastfeeding Women And The Evidence Shows That There Is No Increase In Side Effects In The Infants, Or The Possibility Of Harm To The Breastfed Infants Is Expected To Be Rare. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Drotaverine

No Studies Found