Generic ( Mannitol )

Typical use Of Mannitol :Bladder Irrigation, Cerebral Oedema, Diuresis, Edematous States, Oliguria, Poisoning, Raised Intracranial Pressure, Raised Iop, Renal Insufficiency, Reperfusion Injury, Sodium Depletion.
Mechanism of action of Mannitol :Mannitol Induces Diuresis Because It Is Not Reabsorbed In The Renal Tubule, Thereby Increasing The Osmolality Of The Glomerular Filtrate, Facilitating Excretion Of Water, And Inhibiting The Renal Tubular Reabsorption Of Sodium, Chloride, And Other Solutes. Mannitol Promotes The Urinary Excretion Of Toxic Materials And Protects Against Nephrotoxicity By Preventing The Concentration Of Toxic Substances In The Tubular Fluid.
Drug Interaction of Mannitol :Mannitol Is Known To Interact With Other Drugs Like Cisplatin, Digoxin, Lithium, Metaraminol, Noradrenaline (Acid Tartrate), Potassium Chloride, Sodium Chloride, Streptomycin Sulphate, Suxamethonium (Cl), Tetracycline (HCl). Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Mannitol :Dizziness, Thirst, Headache, Nausea, Vomiting, Fever, Blurred Vision, Chills, Thrombophlebitis, Hypokalemia, Xerostomia, Urinary Retention, Pulmonary Edema, Convulsions, Hypertension, Hypotension, Anaphylaxis.


How Mannitol will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Mannitol will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Mannitol

No Studies Found