Medicine : Mahagesic Plus Nf(110)

Name:Mahagesic Plus Nf(110)
Type:Tablet
Manufacturer:Mankind Pharma
Generic Use:Famotidine , Diclofenac Sodium , Paracetamol
Composition:Famotidine(325mg) , Diclofenac Sodium(50 Mg) , Paracetamol(20 Mg)
Substitutes:mahagesic plus nf(110) , mahagesic plus nf(110) , mahagesic plus nf(110)


Generic ( Famotidine )



Typical use Of Famotidine :Pharmaceutical Aid
Mechanism of action of Famotidine :Famotidine Binds Competitively To H2-receptors Located On The Basolateral Membrane Of The Parietal Cell, Blocking Histamine Affects. This Competitive Inhibition Results In Reduced Basal And Nocturnal Gastric Acid Secretion And A Reduction In Gastric Volume, Acidity, And Amount Of Gastric Acid Released In Response To Stimuli Including Food, Caffeine, Insulin, Betazole, Or Pentagastrin.
Drug Interaction of Famotidine :Famotidine Is Known To Interact With Other Drugs Like Alcohol, Ketoconazole, Magnesium Trisilicate, Probenecid, Sodium Diatrizoate. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Famotidine :Blood Dyscrasias, Hypotension, Tachycardia, Emesis, Restlessness, Dizziness, Headache, Diarrhea, Constipation, Bradycardia, Jaundice, Mental Confusion, Hypotension, Renal Failure.

INTERACTIONS OF FAMOTIDINE


How Famotidine will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Famotidine will impact during lactation(breastfeeding) ?

Safer: Drug Has Been Studied In Few Breastfeeding Women And The Evidence Shows That There Is No Increase In Side Effects In The Infants, Or The Possibility Of Harm To The Breastfed Infants Is Expected To Be Rare. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Famotidine

No Studies Found






Generic ( Diclofenac Sodium )



Typical use Of Diclofenac Sodium :Bacterial Eye Infections And Inflammation
Mechanism of action of Diclofenac Sodium :This Medication Is An NSAID, Prescribed For Severe Pain. This Medication Decreases The Hormones That Cause Inflammation And Pain In The Body.
Drug Interaction of Diclofenac Sodium :Diclofenac, Like Other NSAIDs Is Associated With Several Suspected Or Probable Interactions That Affect The Action Of Other Drugs. Some Examples Are Discussed Below. Diclofenac May Increase The Blood Levels Of Lithium (Eskalith) By Reducing The Excretion Of Lithium By The Kidneys. Increased Levels Of Lithium May Lead To Lithium Toxicity. Diclofenac May Reduce The Blood Pressure Lowering Effects Of Blood Pressure Medications. This May Occur Because Prostaglandins Play A Role In The Regulation Of Blood Pressure. When Diclofenac Is Used In Combination With Aminoglycoside Antibiotics [for Example, Gentamicin (Garamycin)] The Blood Levels Of The Aminoglycoside May Increase, Presumably Because The Elimination Of Aminoglycosides From The Body Is Reduced. This May Lead To More Aminoglycoside-related Side Effects. Individuals Taking Oral Blood Thinners Or Anticoagulants [for Example,warfarin (Coumadin)] Should Avoid Diclofenac Because Diclofenac Also Thins The Blood, And Excessive Blood Thinning May Lead To Bleeding. Combining NSAIDs With Methotrexate (Rheumatrex, Trexall) May Reduce The Elimination Of Methotrexate From The Body And Result In Increased Side Effects From Methotrexate.
Side effects of Diclofenac Sodium :Nausea, Stomach Upset, Skin Rash, Acute Toxicity.

INTERACTIONS OF DICLOFENAC SODIUM


How Diclofenac Sodium will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Diclofenac Sodium will impact during lactation(breastfeeding) ?

Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.

Medicine & Alcohol use and effect of Diclofenac Sodium

No Studies Found






Generic ( Paracetamol )



Typical use Of Paracetamol :Paracetamol Is Used For The Relief Of Mild To Moderate Pain In Conditions Such As Headache (including Migraine), Toothache, Ear Pain, Joint Pain, Pain Of Menstruation, Fever, Feverish Colds, And Flu.
Mechanism of action of Paracetamol :Paracetamol Is Categorized As An Analgesic (painkiller) And Antipyretic (fever Reducing) Drug. Paracetamol Reduces Pain By Increasing The Pain Threshold. It Reduces Fever By Acting On The Temperature-regulating Region Of Brain, Resulting In Increased Blood Flow Across The Skin, Sweating And Heat Loss.
Drug Interaction of Paracetamol :Cholestyramine, Metoclopramide And Domperidone May Alter The Effects Of Paracetamol. Use Of Paracetamol With Warfarin May Increase The Risk Of Bleeding. Paracetamol May Increase The Effects Of Chloramphenicol. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Paracetamol :Side Effects Of Paracetamol Are Usually Rare, And Include Allergic Reactions Such As Shortness Of Breath, Abnormalities Of Blood Cells, Skin Reddening, Blisters Or Rash, Swollen Facial Features, Or A Runny Nose. Overdose (more Than 4 G In Adults And More Than 2 G In Children) May Cause Severe Liver Damage.

INTERACTIONS OF PARACETAMOL


How Paracetamol will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Paracetamol will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Paracetamol

No Studies Found