Generic ( Lovastatin )


Typical use Of Lovastatin :Dysbetalipoproteinemia, Hypercholesterolaemia, Hypertriglyceridaemia, Secondary Hyperlipidemias.
Mechanism of action of Lovastatin :Lovastatin Is A Prodrug That Is Activated In Vivo Via Hydrolysis Of The Lactone Ring To Form The ?-hydroxyacid. The Hydrolyzed Lactone Ring Mimics The Tetrahedral Intermediate Produced By The Reductase Allowing The Agent To Bind To HMG-CoA Reductase With 20,000 Times Greater Affinity Than Its Natural Substrate.
Drug Interaction of Lovastatin :Lovastatin Is Known To Interact With Other Drugs Like Clarithromycin, Cyclosporin A, Itraconazole, Ketoconazole, Mibefradil (Di HCl), Pectin, Pioglitazone, Repaglinide, Silymarin, Warfarin (Na). Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Lovastatin :Weakness, Nausea, Diarrhea, Myalgia, Constipation, Abdominal Pain, Skin Rash, Rhabdomyolysis, Muscle Tenderness, Elevation Of CPK, Muscle Pain.


INTERACTIONS OF LOVASTATIN


How Lovastatin will impact on Pregnancy ?

The Drug Should Not Be Used By Pregnant Women. Experiences Of Drug Use And Evidence From Studies In Pregnant Women Have Shown High Risk To Fetus. The Risk Of Drug Use In Pregnant Women Outweighs The Benefit.

How Lovastatin will impact during lactation(breastfeeding) ?

Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.

Medicine & Alcohol use and effect of Lovastatin

No Studies Found