Generic ( Lomefloxacin )
|Typical use Of Lomefloxacin :||Acute Bacterial Diarrhea, Chronic Bronchitis, Pyelonephritis, Transurethral Surgery, Uncomplicated Cystitis, UTI.|
|Mechanism of action of Lomefloxacin :||The Bactericidal Action Of Lomefloxacin Results From Interference With The Activity Of The Bacterial Enzymes DNA Gyrase And Topoisomerase IV, Which Are Needed For The Transcription And Replication Of Bacterial DNA. DNA Gyrase Appears To Be The Primary Quinolone Target For Gram-negative Bacteria. Topoisomerase IV Appears To Be The Preferential Target In Gram-positive Organisms. Interference With These Two Topoisomerases Results In Strand Breakage Of The Bacterial Chromosome, Supercoiling, And Resealing. As A Result DNA Replication And Transcription Is Inhibited.|
|Drug Interaction of Lomefloxacin :||Lomefloxacin Is Known To Interact With Other Drugs Like Rutin (Vitamin P). These Interactions Are Sometimes Beneficial And Sometimes May Pose Threats To Life. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.|
|Side effects of Lomefloxacin :||Seizures, Tendon Rupture, Dizziness, Vertigo, Headache, Nausea, Anorexia, Diarrhea, Myalgia, Confusion, Pruritus, Hallucination, Asthenia, Phlebitis, Arthralgia, Agitation, Leukopenia.|
INTERACTIONS OF LOMEFLOXACIN
How Lomefloxacin will impact on Pregnancy ?Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.
How Lomefloxacin will impact during lactation(breastfeeding) ?Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.
Medicine & Alcohol use and effect of LomefloxacinNo Studies Found