Generic ( Lamotrigine )


Typical use Of Lamotrigine :Adjunctive Therapy In The Treatment Of Epilepsy In Patients Above 16 Years Of Age In Simple Partial Seizures, Complex Partial Seizures, Secondary Generalised Tonic-clonic Seizures.Bipolar Disorder.
Mechanism of action of Lamotrigine :Lamotrigine Inhibits Voltage-sensitive Sodium Channels And/or Calcium Channels, Thereby Stabilizing Neuronal Membranes And Consequently Modulating Presynaptic Transmitter Release Of Excitatory Amino Acids (e.g., Glutamate And Aspartate).
Drug Interaction of Lamotrigine :Lamotrigine Is Known To Interact With Other Drugs Like Carbamazepine, Fosphenytoin, Phenobarbitone, Phenytoin (Na), Primidone, Sodium Valproate. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Lamotrigine :Ataxia, Thrombocytopenia, Aplastic Anemia, Stevens Johnson Syndrome, Epidermal Necrolysis, Lymphadenopathy, Angioedema, Leucopenia, Neutropenia, Nystagmus, Extrapyramidal Symptoms, Pancytopenia, Dizziness, Headache, Drowsiness, Irritability, Ataxia, Nausea, Fever, Anxiety, Insomnia, Blurred Vision, Maculopapular Rash, Rashes, Sedation, Depression, Tremor.


INTERACTIONS OF LAMOTRIGINE


How Lamotrigine will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Lamotrigine will impact during lactation(breastfeeding) ?

Possibly Unsafe: Evidence From Studies In Breastfeeding Women Show That There Is A Definite Risk Of Side Effects To The Breastfed Infants. However, Use Of The Drug In Breastfeeding Women Is Acceptable In Spite Of The Risk To The Infants, If The Drug Is Needed In A Life-threatening Situation Or For A Serious Disease For Which Safer Drugs Cannot Be Used Or Are Ineffective. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Lamotrigine

No Studies Found