Medicine : Lambin (25inj)

Name:Lambin (25inj)
Manufacturer:Sun Pharmaceutical Industries Ltd
Generic Use:Amphotericin B
Composition:Amphotericin B(25 Mg)
Substitutes:fungisome (25mg) , amphotin lip(25mg) , lambin (25inj)

Generic ( Amphotericin B )

Typical use Of Amphotericin B :Topically For Oral, Vaginal And Cutaneous Candidiasis And Otomycosis. Most Effective For Various Types Of Systemic Mycoses.
Mechanism of action of Amphotericin B :Amphotericin B Is A Polyene Antifungal Antibiotic Which Alters Cell Membrane Permeability By Binding To Ergosterol, Thus Causing Leakage Of Cell Components And Subsequent Cell Death. It Is Active Against Absidia Spp, Aspergillus Spp, Basidiobolus Spp, B. Dermatitidis, Candida Spp, C. Immitis, Conidobolus Spp, C. Neoformans, H. Capsulatum, Mucor Spp, P. Brasiliensis.
Drug Interaction of Amphotericin B :Amphotericin B Is Known To Interact With Other Drugs Like Amikacin (Sulphate), Bendrofluazide, Betamethasone, Calcium Gluconate, Carbenicillin (Na), Carmustine, Chlorothiazide, Chlorthalidone, Cisplatin, Digoxin, Diphenhydramine, Flucytosine, Flucytosine, Foscarnet (Na),gallium Nitrate, Ganciclovir (Na), Hydrochlorothiazide, Hydrocortisone,Kanamycin (Acid Sulphate), Ketoconazole, Lignocaine, Metaraminol.
Side effects of Amphotericin B :Renal Damage, Anaemia, Headache, Nausea, Vomiting, Anorexia, Fever, Abdominal Pain, Chills, Azotemia.


How Amphotericin B will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Amphotericin B will impact during lactation(breastfeeding) ?

Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.

Medicine & Alcohol use and effect of Amphotericin B

No Studies Found