Medicine : Labdic Relief Tab(110)

Name:Labdic Relief Tab(110)
Type:Tablet
Manufacturer:Laborate Pharmaceuticals India Ltd
Generic Use:Chloramphenicol , Diclofenac , Magnesium , Paracetamol
Composition:Chloramphenicol(4 Mg) , Diclofenac(500 Mg) , Magnesium(100 Mg) , Paracetamol(500 Mg)
Substitutes:labdic relief tab(110) , labdic relief tab(110) , labdic relief tab(110) , labdic relief tab(110)


Generic ( Chloramphenicol )



Typical use Of Chloramphenicol :Enteric Fever (Typhoid And Para Typhoid).H.Influenzae Meningitis. Anaerobic Infections, Intraocular Infections, Urinary Tract Infections, Conjunctivitis, External Ear Infections.Corneal Ulcer, Bacterial Conjunctivitis, Trachoma, Ocular Infections.Otitis Externa, Chronic Otitis Media. Pre And Post Antral Or Mastoid Surgery.
Mechanism of action of Chloramphenicol :Chloramphenicol Is Lipid-soluble, Allowing It To Diffuse Through The Bacterial Cell Membrane. It Then Reversibly Binds To The L16 Protein Of The 50S Subunit Of Bacterial Ribosomes, Where Transfer Of Amino Acids To Growing Peptide Chains Is Prevented (perhaps By Suppression Of Peptidyl Transferase Activity), Thus Inhibiting Peptide Bond Formation And Subsequent Protein Synthesis.
Drug Interaction of Chloramphenicol :Chloramphenicol Is Known To Interact With Other Drugs Like Amoxicillin, Ampicillin, Ascorbic Acid, Azlocillin (Na), Bacampicillin, Benzathine Penicillin, Carbenicillin (Na), Chlorpropamide, Chymotrypsin, Cimetidine (HCl), Ciprofloxacin, Cloxacillin, Clozapine, Colistin (Sulphate & Sulphomethate Na), Cyanocobalamin, Cyclophosphamide, Dicloxacillin (Na), Ethinyloestradiol, Floxacillin (Na), Fosphenytoin, Estodene, Glibornuride, Gliquidone, Hydroxocobalamin, Ichthammol, Iron Dextran, Iron Salts, Iron Sorbitol, Mecillinam, Mecobalamin, Nafcillin, Oxacillin, Paracetamol, Phenobarbitone, Phenytoin (Na), Piperacillin (Na),pivmecillinam (HCl), Primidone, Procaine Penicillin, Promethazine (HCl),rifampicin, Sulfapyridine, Tolbutamide, Warfarin (Na).
Side effects of Chloramphenicol :Encephalopathy, Pseudomembranous Colitis, Anemia, Urticaria, Anemia, Thrombocytopenia, Hepatitis, Ototoxicity, Peripheral Neuropathy, Optic Neuritis, Hemolytic Reactions, Interstitial Nephritis, Headache, Nausea, Vomiting, Maculopapular Rash, Stomatitis, Confusion, Pruritus, Depression, Glossitis, Delirium, Transient Stinging.

INTERACTIONS OF CHLORAMPHENICOL


How Chloramphenicol will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Chloramphenicol will impact during lactation(breastfeeding) ?

Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.

Medicine & Alcohol use and effect of Chloramphenicol

No Studies Found






Generic ( Diclofenac )



Typical use Of Diclofenac :Diclofenac Is Used In The Treatment Of Painful Conditions Affecting The Joints And Muscles Such As Degenerative Joint Diseases (osteoarthritis), Autoimmune Diseases Of Joints (rheumatoid Arthritis, Ankylosing Spondylitis) Lower Back Pain, Sprains Or Bone Fractures, Inflammation In And Around Joints (frozen Shoulder), Tendon Inflammation, Tendon Sheath Swelling, Pain And Inflammation Associated With Diseases Such As Gout, Pain And Swelling Following Skeletal Muscle, Dental And Other Minor Surgery.
Mechanism of action of Diclofenac :Diclofenac Works By Blocking The Effect Of Chemicals Called Cyclooxygenase Enzymes. These Enzymes Help To Make Other Chemicals In The Body, Called Prostaglandins. Prostaglandins Are Produced At Sites Of Injury Or Damage, And Cause Pain And Swelling. By Blocking The Effect Of Cyclooxygenase Enzymes, Production Of Prostaglandins Are Reduced, Thus, Pain And Swelling Are Eased. 
Drug Interaction of Diclofenac :Diclofenac Should Be Avoided In Combination With Lithium, Blood Thinning Agents Such As Warfarin, Cyclosporine, Mifepristone, Methotrexate, Selective Serotonin Reuptake Inhibitors, Other Pain Killers, Corticosteroids, Diuretics, Tacrolimus, Zidovudine, And Quinolone Antibiotic Drugs. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Diclofenac :Ulcers In The Stomach And Intestine, Urge To Vomit, Vomiting, Excessive Passage Of Wind, Constipation, Indigestion, Abdominal Pain, Bloody Or Black Tar Like Stools, Vomiting Blood Or Dark Coffee Ground Like Material, Moth Ulcers, Severe Allergic Reactions, Water Retention And Swelling, Rise In Blood Pressure, Heart Failure, Damage To The Kidneys, Elevation Of Liver Enzymes, Inflammation Of Liver, Jaundice, Visual Disturbances, Ringing/buzzing In Ears, Headache, Other Nervous System Disorders, Decrease In The Blood Cells.

INTERACTIONS OF DICLOFENAC


How Diclofenac will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Diclofenac will impact during lactation(breastfeeding) ?

Possibly Unsafe: Evidence From Studies In Breastfeeding Women Show That There Is A Definite Risk Of Side Effects To The Breastfed Infants. However, Use Of The Drug In Breastfeeding Women Is Acceptable In Spite Of The Risk To The Infants, If The Drug Is Needed In A Life-threatening Situation Or For A Serious Disease For Which Safer Drugs Cannot Be Used Or Are Ineffective. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Diclofenac

No Studies Found






Generic ( Magnesium )



Typical use Of Magnesium :Dietary Supplement And Hypomagnesaemia.
Mechanism of action of Magnesium :Magnesium Is Essential To Many Enzymatic Reactions In The Body, Acting As A Cofactor In Protein Synthesis And Carbohydrate Metabolism. 8.36 G Of Magnesium Chloride (hexahydrate) Is Equivalent To About 1 G Of Magnesium. Each G Of Magnesium Chloride (hexahydrate) Represents About 4.9 Mmol Of Magnesium And 9.8 Mmol Of Chloride.
Drug Interaction of Magnesium :Oral Magnesium Salts May Decrease Absorption Of Bisphosphonates, Quinolone Antibiotics And Tetracycline Derivatives
Side effects of Magnesium :Nausea, Stomach Upset, Skin Rash, Acute Toxicity. Watery Diarrhoea, GI Irritation,Nausea, Vomiting, Flushing, Thirst, Hypotension.

INTERACTIONS OF MAGNESIUM


How Magnesium will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Magnesium will impact during lactation(breastfeeding) ?

Safer: Drug Has Been Studied In Few Breastfeeding Women And The Evidence Shows That There Is No Increase In Side Effects In The Infants, Or The Possibility Of Harm To The Breastfed Infants Is Expected To Be Rare. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Magnesium

No Studies Found






Generic ( Paracetamol )



Typical use Of Paracetamol :Paracetamol Is Used For The Relief Of Mild To Moderate Pain In Conditions Such As Headache (including Migraine), Toothache, Ear Pain, Joint Pain, Pain Of Menstruation, Fever, Feverish Colds, And Flu.
Mechanism of action of Paracetamol :Paracetamol Is Categorized As An Analgesic (painkiller) And Antipyretic (fever Reducing) Drug. Paracetamol Reduces Pain By Increasing The Pain Threshold. It Reduces Fever By Acting On The Temperature-regulating Region Of Brain, Resulting In Increased Blood Flow Across The Skin, Sweating And Heat Loss.
Drug Interaction of Paracetamol :Cholestyramine, Metoclopramide And Domperidone May Alter The Effects Of Paracetamol. Use Of Paracetamol With Warfarin May Increase The Risk Of Bleeding. Paracetamol May Increase The Effects Of Chloramphenicol. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Paracetamol :Side Effects Of Paracetamol Are Usually Rare, And Include Allergic Reactions Such As Shortness Of Breath, Abnormalities Of Blood Cells, Skin Reddening, Blisters Or Rash, Swollen Facial Features, Or A Runny Nose. Overdose (more Than 4 G In Adults And More Than 2 G In Children) May Cause Severe Liver Damage.

INTERACTIONS OF PARACETAMOL


How Paracetamol will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Paracetamol will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Paracetamol

No Studies Found