Medicine : Kofend Syp(100ml)

Name:Kofend Syp(100ml)
Type:Syrup
Manufacturer:Nordic Formulations Pvt Ltd (novamed)
Generic Use:Bromhexine , Citric Acid , Diphenhydramine
Composition:Bromhexine(4 Mg) , Citric Acid(60 Mg) , Diphenhydramine(15 Mg)
Substitutes:kofend syp(100ml) , kofend syp(100ml) , kofend syp(100ml)


Generic ( Bromhexine )



Typical use Of Bromhexine :To Clear Mucus From The Respiratory Tract And Mainly Used In Acute And Chronic Respiratory Diseases Such As Bronchitis (inflammation Of Lungs) And Sinusitis (inflammation Of Sinuses).
Mechanism of action of Bromhexine :Bromhexine Works By Thinning The Mucus In The Airways, Thus Making The Mucus Less Sticky And Facilitating The Removal Of The Mucus.
Drug Interaction of Bromhexine :No Clinically Relevant Unfavorable Interactions With Other Medications Have Been Reported. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Bromhexine :May Cause Gastric Disturbances Such As Diarrhea, Urge To Vomit (nausea), Vomiting, Indigestion, Bloating And Other Mild Stomach Side Effects, Dizziness, Headache, Sweating And Skin Rashes.

INTERACTIONS OF BROMHEXINE


How Bromhexine will impact on Pregnancy ?

There Is Sufficient Evidence To Suggest That There Is No Risk To The Fetus In The First Trimester (12 Weeks) Of Pregnancy And There Is No Evidence Of Risk In Later Trimesters. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Bromhexine will impact during lactation(breastfeeding) ?

Safest: Evidence From Clinical Studies Has Shown That This Drug When Taken By Breastfeeding Mothers Has Not Shown Any Major Side Effects In Infants. The Possibility Of Harm To The Breastfed Infants Is Expected To Be Rare Or The Drug Does Not Reach The Infant Through Breast Milk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Bromhexine

No Studies Found






Generic ( Citric Acid )



Typical use Of Citric Acid :Urinary Alkalinization.
Mechanism of action of Citric Acid :Citrate Salts Are Alkalinisers. They Are Commonly Used In Situations Where Long-term Maintenance Of An Alkaline Urine Is Necessary And In The Management Of Chronic Metabolic Acidosis. Citric Acid Is Also Used In Effervescing Mixtures And As A Synergist To Improve The Efficacy Of Antioxidants. It May Also Be Used In Preparations That Are Used In The Treatment Of Dry Mouth And To Dissolve Renal Calculi And Prevent Encrustation Of Urinary Catheters.
Drug Interaction of Citric Acid :Citric Acid Is Known To Interact With Other Drugs Like Aluminium Hydroxide And Oxide. These Interactions Are Sometimes Beneficial And Sometimes May Pose Threats To Life. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Citric Acid :Local Irritation, Erosion Of Teeth.

INTERACTIONS OF CITRIC ACID


How Citric Acid will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Citric Acid will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Citric Acid

No Studies Found






Generic ( Diphenhydramine )



Typical use Of Diphenhydramine :Allergy, Hay Fever, Urticaria And Rhinitis.
Mechanism of action of Diphenhydramine :Diphenhydramine Competes With Free Histamine For Binding At HA-receptor Sites. This Antagonizes The Effects Of Histamine On HA-receptors, Leading To A Reduction Of The Negative Symptoms Brought On By Histamine HA-receptor Binding.
Drug Interaction of Diphenhydramine :Diphenhydramine Is Known To Interact With Other Drugs Like Alcohol, Amphotericin B, Atomoxetine HCl, Atropine (Sulphate), Nabilone, Oxymorphone, Pericyazine, Rizatriptan. These Interactions Are Sometimes Beneficial And Sometimes May Pose Threats To Life. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Diphenhydramine :Flushing, Nausea, Tachycardia, Convulsions, Coma, Drowsiness, Dry Mouth, Urinary Retention, Hallucinations, Dizziness, Tiredness, Ataxia, Tremors, Nervousness, Tinnitus, Blurred Vision, Sedation, Diplopia, Euphoria.

INTERACTIONS OF DIPHENHYDRAMINE


How Diphenhydramine will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Diphenhydramine will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Diphenhydramine

No Studies Found