Generic ( Ketoprofen )


Typical use Of Ketoprofen : Analgesic, Antipyretic, Dysmenorrhoea, Rheumatoid Arthritis, Osteoarthritis, Musculo Skeletal Disorders, Soft Tissue Injuries, Tooth Extraction, Post-partum And Post Operatively, Acute Gout.
Mechanism of action of Ketoprofen :Ketoprofen Exhibits Anti-inflammatory, Analgesic And Antipyretic Activities. It Potently Inhibits The Enzyme Cyclooxygenase Resulting In Prostaglandin Synthesis Inhibition. It Also Prevents Formation Of Thromboxane A2 By Platelet Aggregation
Drug Interaction of Ketoprofen :Ketoprofen May Increase The Blood Levels Of Lithium (Eskalith) By Reducing The Excretion Of Lithium By The Kidneys Which May Lead To Lithium Toxicity.Ketoprofen May Reduce The Blood Pressure Lowering Effects Of Blood Pressure Medications. This Occurs Because Prostaglandins Play A Role In Reducing Blood Pressure.When NSAIDs Are Combined With Methotrexate (Rheumatrex, Trexall) Or Aminoglycosides (for Example, Gentamicin) The Blood Levels Of Methotrexate Or Aminoglycoside May Increase Because The Elimination Of Methotrexate And Aminoglycosides Is Reduced. This May Lead To More Methotrexate Or Aminoglycoside Side Effects.Individuals Taking Blood Thinners Or Anticoagulants, For Example, Warfarin (Coumadin), Should Avoid Ketoprofen Because Ketoprofen Also Thins The Blood, And Excessive Blood Thinning May Lead To Bleeding.Persons Who Have More Than Three Alcoholic Beverages Per Day Are At Increased Risk Of Developing Stomach Ulcers When Taking Ketoprofen Or Other NSAIDs.
Side effects of Ketoprofen :Reduced GFR (glomerular Filtration Rate), Acute Interstitial Nephritis, Platelet Dysfunction.


INTERACTIONS OF KETOPROFEN


How Ketoprofen will impact on Pregnancy ?

Experiences Of Drug Use And Evidence From Studies In Pregnant Women Have Shown Risk To Fetus. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Ketoprofen will impact during lactation(breastfeeding) ?

Possibly Unsafe: Evidence From Studies In Breastfeeding Women Show That There Is A Definite Risk Of Side Effects To The Breastfed Infants. However, Use Of The Drug In Breastfeeding Women Is Acceptable In Spite Of The Risk To The Infants, If The Drug Is Needed In A Life-threatening Situation Or For A Serious Disease For Which Safer Drugs Cannot Be Used Or Are Ineffective. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Ketoprofen

No Studies Found