Medicine : Jorni Tab
|Manufacturer:||Zydus Cadila Healthcare Ltd (german Remedies)|
|Generic Use:||Nitazoxanide , Ofloxacin|
|Composition:||Nitazoxanide(500 Mg) , Ofloxacin(100 Mg)|
|Substitutes:||jorni tab , jorni tab|
Generic ( Nitazoxanide )
|Typical use Of Nitazoxanide :||Giardiasis, E.histolytics, T Vaginalis, Cryptosporidium, H. Pylori, Ascaria, H. Nana And Enterobius Vermicularis, Trichuris And Trichura.|
|Mechanism of action of Nitazoxanide :||This Medication Is Taken Up By Diffusion, Is Selectively Absorbed By Anaerobic Bacteria And Sensitive Protozoa. Once Taken Up By Anaerobes, It Is Non-enzymatically Reduced By Reacting With Reduced Ferredoxin, Which Is Generated By Pyruvate Oxido-reductase. Many Of The Reduced Nitroso Intermediates Will Form Sulfinamides And Thioether Linkages With Cysteine Bearing Enzymes Deactivating These Critical Enzymes. As Many As 150 Separate Enzymes Are Affected.|
|Drug Interaction of Nitazoxanide :||Nitazoxanide Is Known To Interact With Other Drugs Like Warfarin (Na).|
|Side effects of Nitazoxanide :||Nausea, Stomach Upset, Skin Rash, Acute Toxicity.|
INTERACTIONS OF NITAZOXANIDE
How Nitazoxanide will impact on Pregnancy ?Experiences Of Drug Use And Evidence From Studies In Pregnant Women Have Shown Risk To Fetus. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.
How Nitazoxanide will impact during lactation(breastfeeding) ?Possibly Unsafe: Evidence From Studies In Breastfeeding Women Show That There Is A Definite Risk Of Side Effects To The Breastfed Infants. However, Use Of The Drug In Breastfeeding Women Is Acceptable In Spite Of The Risk To The Infants, If The Drug Is Needed In A Life-threatening Situation Or For A Serious Disease For Which Safer Drugs Cannot Be Used Or Are Ineffective. Patients Should Follow The Advice Of The Doctor Regarding Its Use.
Medicine & Alcohol use and effect of NitazoxanideNo Studies Found
Generic ( Ofloxacin )
|Typical use Of Ofloxacin :||To Treat Bacterial Infections Including Urinary Tract Infections, Respiratory Infections , Skin And Soft Tissue Infections, Sexually Transmitted Infections (of Urethra And Cervix) And External Eye Infections (conjuctivitis).|
|Mechanism of action of Ofloxacin :||Ofloxacin Belongs To The Group Of Medicines Called Fluoroquinolone Antibiotics. They Cure The Infection By Inhibiting The DNA Formation And Killing The Bacteria.|
|Drug Interaction of Ofloxacin :||Ofloxacin May Interact With Other Drugs Including Drugs That Are Used To Treat The Abnormal Rate And Rhythm Of Heart (antiarrythmics Viz Quindine, Hydroquindine, Disopyramide, Amiodarone, Sotalol, Dofetilide, Ibutilide), Tricyclic Anti-depressants , Antibiotics (azithromycin) And Some Anti-psychotics. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.|
|Side effects of Ofloxacin :||When Used As Eye-drops, Side Effects Include Visual Disturbance, Tearing, Mild Stinging, Burning Or Pricking, Irritation, Ocular Discomfort, Inflammation, Redness, Itching, Allergic Reactions In The Eye (including Itchiness Of The Eye And Eyelid), Sensitivity To Light, Eye Swelling. When Used Orally, Side Effects Include Dizziness, Nausea, Allergic Reactions (swelling Of Face, Lips Or Other Parts Of The Body; Rash Or Itching On The Skin; Swelling Of The Mouth, Tongue Or Throat That Can Obstruct The Airways Which May Cause Wheezing, Difficulty Swallowing, Breathing Or Shortness Of Breath; Severe Sudden Life-threatening Allergic Reaction), Swelling Of The Face.|
INTERACTIONS OF OFLOXACIN
How Ofloxacin will impact on Pregnancy ?Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.
How Ofloxacin will impact during lactation(breastfeeding) ?Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.
Medicine & Alcohol use and effect of OfloxacinNo Studies Found