Medicine : Istamet 50/(500mg)

Name:Istamet 50/(500mg)
Type:Tablet
Manufacturer:Sun Pharmaceutical Industries Ltd
Generic Use:Metformin , Sitagliptin
Composition:Metformin() , Sitagliptin()
Substitutes:istamet 50/(500mg) , istavel 50/(100mg) , istamet 50/(500mg) , istavel 50/(100mg)


Generic ( Metformin )



Typical use Of Metformin :Metformin Is Used In The Treatment Of Diabetes Mellitus, Insulin Resistance, And Obesity.
Mechanism of action of Metformin :The Exact Mechanism Of Action Of Metformin Is Not Clear But It Appears To Act By Decreasing Glucose Absorption From The Intestine, Decreasing Production Of Glucose From Proteins And Fats In Liver, And Enhancing Insulin Sensitivity In Muscle By Increasing Glucose Uptake And Utilization.
Drug Interaction of Metformin :Taking Metformin With Other Anti-diabetic Drugs May Lead To Excessive Lowering Of Bloodsugar. If You Go For An X-ray Or Scan, Do Not Take Metformin Before And At Least 48 Hours Afterwards. Metformin With Diuretics (furosemide), Anti-asthmatic Drugs Such As Salbutamol Or Terbutaline, Or Corticosteroids (prednisone) May Affect The Glucose Control. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Metformin :The Common Side Effects Are Urge To Vomit, Vomiting, Diarrhea, Abdominal Pain, Loss Of Appetite, Malabsorption Of Vitamin B12, Taste Disturbance, And Altered Liver Functions. Also, The Patient May Have The Side Effects Of Lactic Acidosis (symptoms Are Vomiting, Abdominal Pain With Muscle Cramps, Not Feeling Well With Severe Tiredness, And Difficulty In Breathing), And Skin Reactions Such As Redness Of Skin, Itching, Hives (pale Red, Raised, Itchy Bumps Of Skin).

INTERACTIONS OF METFORMIN


How Metformin will impact on Pregnancy ?

The Drug Should Not Be Used By Pregnant Women. Experiences Of Drug Use And Evidence From Studies In Pregnant Women Have Shown High Risk To Fetus. The Risk Of Drug Use In Pregnant Women Outweighs The Benefit.

How Metformin will impact during lactation(breastfeeding) ?

Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.

Medicine & Alcohol use and effect of Metformin

No Studies Found






Generic ( Sitagliptin )



Typical use Of Sitagliptin :Sitagliptin Is Used To Lower Blood Sugar Levels In Adult Patients With Type 2 Diabetes Mellitus.
Mechanism of action of Sitagliptin :Sitagliptin Blocks The Action Of A Certain Enzyme (dipeptidyl Peptidase-4) And Prolongs The Action Of Hormones Involved In The Release Of Insulin, Thereby Reducing Blood Glucose Levels.
Drug Interaction of Sitagliptin :Sitagliptin In Combination With Other Anti-diabetic Drugs May Cause Excessive Lowering Of Blood Sugar. It May Interact With Other Drugs Including Ketoconazole, Ritonavir, Clarithromycin, Probenecid, And Digoxin. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Sitagliptin :Low Blood Sugar, Urge To Vomit, Vomiting, Excessive Passage Of Wind Or Gas, Inflammation Of The Pancreas (manifests As Sever And Persistent Pain In Abdomen, Which May Reach Up To The Back, Associated With An Urge To Vomit Or Frank Vomiting). Contact You Doctor Immediately If Serious Allergic Reaction Including Rash, Hives, Swelling Of The Face, Lips, Tongue, And Throat With Difficulty In Breathing Or Swallowing Develops.

INTERACTIONS OF SITAGLIPTIN


How Sitagliptin will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Sitagliptin will impact during lactation(breastfeeding) ?

Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.

Medicine & Alcohol use and effect of Sitagliptin

No Studies Found