Medicine : Ismo (20mg)

Name:Ismo (20mg)
Manufacturer:Nicholas Piramal India Ltd
Generic Use:Isosorbide Mononitrate
Composition:Isosorbide Mononitrate(5 Mononitrate) , Isosorbide Mononitrate(20 Mg)
Substitutes:ismo (20mg) , monn (20mg) , ismo (20mg) , monn (20mg)

Generic ( Isosorbide Mononitrate )

Typical use Of Isosorbide Mononitrate :For The Prevention Of Angina Pectoris Due To Coronary Artery Disease And The Treatment Of Acute And Chronic Angina Pectoris, Hypertension, And Myocardial Infarction.
Mechanism of action of Isosorbide Mononitrate :Isosorbide Mononitrate Is Converted To Nitric Oxide (NO), An Active Intermediate Compound Which Activates The Enzyme Guanylate Cyclase (Atrial Natriuretic Peptide Receptor A). This Stimulates The Synthesis Of Cyclic Guanosine 3',5'-monophosphate (cGMP) Which Then Activates A Series Of Protein Kinase-dependent Phosphorylations In The Smooth Muscle Cells, Eventually Resulting In The Dephosphorylation Of The Myosin Light Chain Of The Smooth Muscle Fiber. The Subsequent Release Of Calcium Ions Results In The Relaxation Of The Smooth Muscle Cells And Vasodilation.
Drug Interaction of Isosorbide Mononitrate :Isosorbide Mononitrate Is Known To Interact With Other Drugs Like Avanafil, Dihydroergotamine, Dihydroergotoxine, Ergonovine, Methylergonovine, Sildenafil, Telithromycin, Udenafil, Voriconazole. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Isosorbide Mononitrate :Tachycardia, Flushing, Headache, Dizziness, Palpitation, Syncope, Confusion, Nausea, Vomiting, Abdominal Pain, Restlessness, Weakness And Vertigo, Dry Mouth, Chest Pain, Back Pain, Oedema, Fatigue, Abdominal Pain, Constipation, Diarrhoea.


How Isosorbide Mononitrate will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Isosorbide Mononitrate will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Isosorbide Mononitrate

No Studies Found