Medicine : Ipofos With Mesna(2gm)

Name:Ipofos With Mesna(2gm)
Type:Injection
Manufacturer:Getwell Pharmaceuticals
Generic Use:Ifosfamide , Mesna
Composition:Ifosfamide(2 Mg) , Mesna(1200 Mg)
Substitutes:ipofos with mesna(2gm) , ipofos with mesna(2gm)


Generic ( Ifosfamide )



Typical use Of Ifosfamide :Breast Cancer, Cervical Carcinoma, Chronic Lymphocytic Leukaemia, Lung Cancer, Ovarian Cancer, Soft Tissue Sarcoma, Testicular Cancer
Mechanism of action of Ifosfamide :Ifosfamide Is Converted To Its Active Metabolites Via Hepatic Microsomal Enzymes. These Active Metabolites Act As Alkylating Agents, Disrupting DNA And Protein Synthesis Of The Target Cells. It Is Routinely Given With Mesna To Reduce Urothelial Toxicity.
Drug Interaction of Ifosfamide :Not Known
Side effects of Ifosfamide :Drowsiness, Ataxia, Nausea, Vomiting, Alopecia, Confusion, Dysuria, Azotemia.

INTERACTIONS OF IFOSFAMIDE


How Ifosfamide will impact on Pregnancy ?

Experiences Of Drug Use And Evidence From Studies In Pregnant Women Have Shown Risk To Fetus. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Ifosfamide will impact during lactation(breastfeeding) ?

Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.

Medicine & Alcohol use and effect of Ifosfamide

No Studies Found






Generic ( Mesna )



Typical use Of Mesna :Cyclophosphamide Induced Hemorrhagic Cystitis, Ifosfamide Induced Hemorrhagic Cystitis, Prostate Cancer.
Mechanism of action of Mesna :Mesna Reacts With Acrolein And Other Urotoxic Metabolites Of Oxazaphosphorines (cyclophosphamide Or Ifosfamide) In The Urine To Form Stable, Nonurotoxic Compounds. Mesna Does Not Have Any Antitumour Activity, Nor Does It Appear To Interfere With The Antitumour Activity Of Antineoplastic Drugs.
Drug Interaction of Mesna :Tell Your Doctor Of All Prescription And Nonprescription Medication You May Use. Do Not Start Or Stop Any Medicine Without Doctor Or Pharmacist Approval.
Side effects of Mesna :Headache, Diarrhea, Tachycardia, Abdominal Pain, Hypotension, Cough, Bronchospasm, Limb Pain, Joint Pain, Exhaustion, Yellowing Of Teeth.

INTERACTIONS OF MESNA


How Mesna will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Mesna will impact during lactation(breastfeeding) ?

Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.

Medicine & Alcohol use and effect of Mesna

No Studies Found