Medicine : Insuman (25/75inj 10ml)

Name:Insuman (25/75inj 10ml)
Type:Injection
Manufacturer:Sanofi India Ltd (aventis)
Generic Use:Insulin Isophane , Insulin
Composition:Insulin Isophane(75%) , Insulin(25%)
Substitutes:insuman (25/75inj 10ml) , insuman (25/75inj 10ml)


Generic ( Insulin Isophane )



Typical use Of Insulin Isophane :Diabetes Mellitus.
Mechanism of action of Insulin Isophane :Insulin Isophane Binds To The Insulin Receptor (IR), A Heterotetrameric Protein Consisting Of Two Extracellular Alpha Units And Two Transmembrane Beta Units. The Binding Of Insulin To The Alpha Subunit Of IR Stimulates The Tyrosine Kinase Activity Intrinsic To The Beta Subunit Of The Receptor. The Bound Receptor Is Able To Autophosphorylate And Phosphorylate Numerous Intracellular Substrates Such As Insulin Receptor Substrates (IRS) Proteins, Cbl, APS, Shc And Gab 1. These Activated Proteins, In Turn, Lead To The Activation Of Downstream Signaling Molecules Including PI3 Kinase And Akt. Akt Regulates The Activity Of Glucose Transporter 4 (GLUT4) And Protein Kinase C (PKC) Which Play A Critical Role In Metabolism And Catabolism.
Drug Interaction of Insulin Isophane :Insulin Isophane Is Known To Interact With Other Drugs Like MAOIs, ACE Inhibitors, Salicylates, Alcohol, Anabolic Steroids And Non-selective β-blockers. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Insulin Isophane :Injection Site Reactions E.g. Swelling, Redness, Itch And Pain.

INTERACTIONS OF INSULIN ISOPHANE


How Insulin Isophane will impact on Pregnancy ?

There Are No Studies Available Regarding Its Use During Pregnancy. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Insulin Isophane will impact during lactation(breastfeeding) ?

There Are No Studies Available Regarding Its Use During Lactation. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Insulin Isophane

No Studies Found






Generic ( Insulin )



Typical use Of Insulin : Diabetes Mellitus, Hyperkalaemia, Iddm.
Mechanism of action of Insulin :Insulin Lowers Blood Glucose Levels. It Regulates Carbohydrate, Protein And Fat Metabolism By Inhibiting Hepatic Glucose Production And Lipolysis, And Enhancing Peripheral Glucose Disposal.
Drug Interaction of Insulin :Insulin Is Known To Interact With Other Drugs Like Acarbose, Nicotine, Oxprenolol, Oxymetholone, Psyllium Husk, Sodium Calciumedetate, Somatostatin, Somatropin. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Insulin :Hypoglycaemia, Insulin Resistance, Lipoatrophy, Hypokalaemia, Blurred Vision.

INTERACTIONS OF INSULIN


How Insulin will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Insulin will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Insulin

No Studies Found