Medicine : Imuza (50mg)

Name:Imuza (50mg)
Manufacturer:Panacea Biotec Ltd
Generic Use:Azathioprine
Composition:Azathioprine(50 Mg)

Generic ( Azathioprine )

Typical use Of Azathioprine :Renal Transplantation. Autoimmune Diseases. Severe Rheumatoid Arthritis Unresponsive To Other Drugs.
Mechanism of action of Azathioprine :Azathioprine Is An Imidazolyl Derivative Of Mercaptopurine, Which Inhibits DNA, RNA And Protein Synthesis And Antagonises Purine Synthesis. It Also Inhibits Mitosis And Interferes With Cellular Metabolism Of Susceptible Organisms. Azathioprine Inj Should Be Converted To Oral Therapy As Soon As The Drug Can Be Tolerated.
Drug Interaction of Azathioprine :Allopurinol That Is Used For Treating Increased Blood Levels Of Uric Acid And Preventing Gout Increases Azathioprine Levels In The Blood Which May Increase The Risk Of Side Effects From Azathioprine. Therefore, It Is Important To Reduce The Dose Of Azathioprine By Approximately 1/3 To 1/4 In Patients Taking Allopurinol. The Use Of Angiotensin-converting Enzyme (ACE) Inhibitors To Control High Blood Pressure In Patients Taking Azathioprine Has Been Reported To Induceanemia (low Levels Of Red Blood Cells) And Severe Leukopenia (low Levels Of White Blood Cells). Azathioprine Reduces Blood Levels Of The Blood Thinner,warfarin (Coumadin), And Thus May Reduce The Blood Thinning Effect Of Warfarin. Safety And Efficacy Of Azathioprine In Children Have Not Been Established
Side effects of Azathioprine :Fever, Chills, Bone Marrow Depression Characterised By Leucopenia, Thrombocytopenia Or Anaemia, Anorexia, Nausea, Diarrhoea, Arthralgias, Secondary Infections, Hepatotoxicity, Rash, Alopoecia.


How Azathioprine will impact on Pregnancy ?

Information Not Available.

How Azathioprine will impact during lactation(breastfeeding) ?

Information Not Available.

Medicine & Alcohol use and effect of Azathioprine

Information Not Available.