Medicine : Imograf Oint(15gm)

Name:Imograf Oint(15gm)
Type:Ointment
Manufacturer:Canixa Life Sciences Pvt Ltd
Generic Use:Tacrolimus
Composition:Tacrolimus(15 G)
Substitutes:imograf oint(15gm)


Generic ( Tacrolimus )



Typical use Of Tacrolimus :Atopic Dermatitis, Kidney Transplantation, Liver Transplantation.
Mechanism of action of Tacrolimus :Tacrolimus Bind To Cytosolic Receptors Known As Immunophilins (i.e., Cyclophilin And FK Binding Protein-12 [FKBP-12], Respectively), Forming Complexes That Inhibit The Production Of Cytokines Via The Calcineurin Pathway. Inhibition Of Calcineurin Activity Inhibits Early Activation Of T-cells (ie.immunosuppresion Results).
Drug Interaction of Tacrolimus :Tacrolimus Is Known To Interact With Other Drugs Like Amiloride (HCl), Amphotericin B, Azapropazone, Carbamazepine, Cisplatin, Clarithromycin, Danazol, Ergotamine (Tartrate), Erythromycin, Ganciclovir (Na), Isoniazid, Ketoconazole, Methylprednisolone, Mumps Vaccine, Oxaliplatin, Phenobarbitone, Phenytoin (Na), Rifampicin, Ritonavir, Spironolactone, Triamterene. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Berequired.
Side effects of Tacrolimus :Hallucinations, Tachycardia, Confusion, Anxiety, Leucopenia, Renal Failure, Hyperglycemia, Hypertension, Angina, Leucocytosis, Tremors, Oliguria, Renal Insufficiency.

INTERACTIONS OF TACROLIMUS


How Tacrolimus will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Tacrolimus will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Tacrolimus

No Studies Found