Medicine : Imicila (250mg)

Name:Imicila (250mg)
Type:Injection
Manufacturer:Piramal Healthcare
Generic Use:Cilastatin , Imipenem
Composition:Cilastatin(250mg) , Imipenem(250mg)
Substitutes:cilanem (250mg) , i nem(250mg) , icl (500mg) , ime cila(250mg) , imicila (250mg) , imicrit (250mg) , amcyl (500mg) , cilanem (250mg) , i nem(250mg) , icl (500mg) , ime cila(250mg) , imicila (250mg) , imicrit (250mg) , amcyl (500mg)


Generic ( Cilastatin )



Typical use Of Cilastatin :Small Cell Carcinoma.
Mechanism of action of Cilastatin :Cilastatin Is A Specific And Reversible Renal Dehydropeptidase-I Inhibitor. Cilastatin Prevents The Metabolism Of Leukotriene D4 To Leukotriene E4 Through The Inhibition Of Leukotriene D4 Dipeptidase.
Drug Interaction of Cilastatin :Cilastatin Is Known To Interact With Other Drugs Like Cyclosporine, Valganciclovir. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Cilastatin :Diarrhea, Fever, Rashes, Confusion, Allergic Reactions, Nausea And Vomiting, Hearing Loss, Taste Disturbance, Blood Disorders, Tooth And Tongue Discoloration.

INTERACTIONS OF CILASTATIN


How Cilastatin will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Cilastatin will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Cilastatin

No Studies Found






Generic ( Imipenem )



Typical use Of Imipenem :Abdominal Sepsis, Advanced Prostate Cancer, Bone And Joint Infection, Brain Abscesses, Cellulitis, Diabetic Foot Ulcer, Endocarditis, Gastric Acid Reduction During General Anaesthesia, Gynecological Infections, Lower Respiratory Tract Infections, Obstetric Infections, Peritonitis.
Mechanism of action of Imipenem :Imipenem Acts As An Antimicrobial Through The Inhibition Of Cell Wall Synthesis Of Various Gram-positive And Gram-negative Bacteria. This Inhibition Of Cell Wall Synthesis In Gram-negative Bateria Is Attained By Binding To Pencillin Binding Proteins (PBPs).
Drug Interaction of Imipenem :Imipenem Is Known To Interact With Other Drugs Like Ganciclovir (Na), Probenecid. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Imipenem :Thrombocytopenia, Seizures, Renal Impairment, Leukopenia, Dizziness, Diarrhea, Allergic Reactions, Glossitis, Hypersalivation.

INTERACTIONS OF IMIPENEM


How Imipenem will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Imipenem will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Imipenem

No Studies Found