Medicine : Idromet (50mg)

Name:Idromet (50mg)
Manufacturer:Aureate Pharma
Generic Use:Ibandronate
Composition:Ibandronate(50 Mg)
Substitutes:idrofos (50mg) , idrofos (50) , idrofos kit(50mg) , idromet (50mg)

Generic ( Ibandronate )

Typical use Of Ibandronate :Hypercalcaemia Due To Malignancy, Hypercalcaemia Of Malignancy.
Mechanism of action of Ibandronate :The Action Of Ibandronate On Bone Tissue Is Based Partly On Its Affinity For Hydroxyapatite, Which Is Part Of The Mineral Matrix Of Bone. Nitrogen-containing Bisphosphonates (such As Pamidronate, Alendronate, Risedronate, Ibandronate And Zoledronate) Appear To Act As Analogues Of Isoprenoid Diphosphate Lipids, Thereby Inhibiting Farnesyl Pyrophosphate (FPP) Synthase, An Enzyme In The Mevalonate Pathway. Inhibition Of This Enzyme In Osteoclasts Prevents The Biosynthesis Of Isoprenoid Lipids (FPP And GGPP) That Are Essential For The Post-translational Farnesylation And Geranylgeranylation Of Small GTPase Signalling Proteins. This Activity Inhibits Osteoclast Activity And Reduces Bone Resorption And Turnover.
Drug Interaction of Ibandronate :Hypercalcaemia Due To Malignancy, Hypercalcaemia Of Malignancy.
Side effects of Ibandronate :Fever, Chills, Bone Pain, Influenza Like Syndrome, Hypersensitivity Reactions, Bronchospasm, Angioedema, Muscle Pain.


How Ibandronate will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Ibandronate will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Ibandronate

No Studies Found