Medicine : Halotop S Oint(30gm)

Name:Halotop S Oint(30gm)
Manufacturer:Ipca Laboratories Ltd
Generic Use:Halobetasol

Generic ( Halobetasol )

Typical use Of Halobetasol :Used For The Relief Of The Inflammatory And Pruritic Manifestations.
Mechanism of action of Halobetasol :Halobetasol Propionate Is Thought To Act By The Induction Of Phospholipase A2 Inhibitory Proteins, Collectively Called Lipocortins. These Proteins Control The Biosynthesis Of Potent Mediators Of Inflammation Such As Prostaglandins And Leukotrienes By Inhibiting The Release Of Their Common Precursor Arachidonic Acid. Arachidonic Acid Is Released From Membrane Phospholipids By Phospholipase A2. The Initial Interaction, However, Is Due To The Drug Binding To The Cytosolic Glucocorticoid Receptor. After Binding The Receptor The Newly Formed Receptor-ligand Complex Translocates Itself Into The Cell Nucleus, Where It Binds To Many Glucocorticoid Response Elements (GRE) In The Promoter Region Of The Target Genes. The DNA Bound Receptor Then Interacts With Basic Transcription Factors, Causing The Increase In Expression Of Specific Target Genes.
Drug Interaction of Halobetasol :Used For The Relief Of The Inflammatory And Pruritic Manifestations.
Side effects of Halobetasol :Pustulation, Erythema, Skin Atrophy, Leukoderma, Acne, Itching, Secondary Infection, Telangiectasia, Urticaria, Dry Skin, Miliaria, Paresthesia, And Rash.


How Halobetasol will impact on Pregnancy ?

Information Not Available.

How Halobetasol will impact during lactation(breastfeeding) ?

Information Not Available.

Medicine & Alcohol use and effect of Halobetasol

Information Not Available.