Medicine : Halosys S Lotion(20ml)

Name:Halosys S Lotion(20ml)
Type:Syrup
Manufacturer:Systopic Laboratories Pvt Ltd
Generic Use:Halobetasol , Salicylic Acid
Composition:Halobetasol(0.05%) , Salicylic Acid(3%)
Substitutes:halosys s lotion(20ml) , halosys s lotion(20ml)


Generic ( Halobetasol )



Typical use Of Halobetasol :Used For The Relief Of The Inflammatory And Pruritic Manifestations.
Mechanism of action of Halobetasol :Halobetasol Propionate Is Thought To Act By The Induction Of Phospholipase A2 Inhibitory Proteins, Collectively Called Lipocortins. These Proteins Control The Biosynthesis Of Potent Mediators Of Inflammation Such As Prostaglandins And Leukotrienes By Inhibiting The Release Of Their Common Precursor Arachidonic Acid. Arachidonic Acid Is Released From Membrane Phospholipids By Phospholipase A2. The Initial Interaction, However, Is Due To The Drug Binding To The Cytosolic Glucocorticoid Receptor. After Binding The Receptor The Newly Formed Receptor-ligand Complex Translocates Itself Into The Cell Nucleus, Where It Binds To Many Glucocorticoid Response Elements (GRE) In The Promoter Region Of The Target Genes. The DNA Bound Receptor Then Interacts With Basic Transcription Factors, Causing The Increase In Expression Of Specific Target Genes.
Drug Interaction of Halobetasol :Used For The Relief Of The Inflammatory And Pruritic Manifestations.
Side effects of Halobetasol :Pustulation, Erythema, Skin Atrophy, Leukoderma, Acne, Itching, Secondary Infection, Telangiectasia, Urticaria, Dry Skin, Miliaria, Paresthesia, And Rash.

INTERACTIONS OF HALOBETASOL


How Halobetasol will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Halobetasol will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Halobetasol

No Studies Found






Generic ( Salicylic Acid )



Typical use Of Salicylic Acid :Hyperkeratotic And Scaling Skin Conditions, Acne, Warts And Calluses.
Mechanism of action of Salicylic Acid :Salicylic Acid Has A Potent Keratolytic Action And A Slight Antiseptic Action When Applied Topically. It Softens And Destroys The Stratum Corneum By Increasing Endogenous Hydration Which Causes The Horny Layer Of The Skin To Swell, Soften, And Then Desquamate. At High Concentrations, Salicylic Acid Has A Caustic Effect. It Also Possesses Weak Antifungal And Antibacterial Activity.
Drug Interaction of Salicylic Acid :Hyperkeratotic And Scaling Skin Conditions, Acne, Warts And Calluses.
Side effects of Salicylic Acid :Irritation, Sensitivity, Excessive Drying; Systemic Effects On Prolonged Use.

INTERACTIONS OF SALICYLIC ACID


How Salicylic Acid will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Salicylic Acid will impact during lactation(breastfeeding) ?

Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.

Medicine & Alcohol use and effect of Salicylic Acid

No Studies Found