Generic ( Granisetron )


Typical use Of Granisetron :Nausea And Vomiting Induced By Cytotoxic Chemotherapy And Radiotherapy.Prophylaxis And Treatment Of Postoperative Nausea And Vomiting.
Mechanism of action of Granisetron :Granisetron Is A Potent, Selective Antagonist Of 5-HT3 Receptors. The Antiemetic Activity Of The Drug Is Brought About Through The Inhibition Of 5-HT3 Receptors Present Both Centrally (medullary Chemoreceptor Zone) And Peripherally (GI Tract). This Inhibition Of 5-HT3 Receptors In Turn Inhibits The Visceral Afferent Stimulation Of The Vomiting Center, Likely Indirectly At The Level Of The Area Postrema, As Well As Through Direct Inhibition Of Serotonin Activity Within The Area Postrema And The Chemoreceptor Trigger Zone.
Drug Interaction of Granisetron :Granisetron Is Known To Interact With Other Drugs Like Dexamethasone. These Interactions Are Sometimes Beneficial And Sometimes May Pose Threats To Life. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Granisetron :Headache, Sensation Of Flushing, Constipation, Hypersensitivity Reactions, Chest Pain, CV Disturbances, Dizziness, Transient Visual Disturbances.


INTERACTIONS OF GRANISETRON


How Granisetron will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Granisetron will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Granisetron

No Studies Found