Generic ( Gramicidin )


Typical use Of Gramicidin :Superficial Infections.
Mechanism of action of Gramicidin :Gramicidin Binds To And Inserts Itself Into Bacterial Membranes. This Results In Membrane Disruption And Permeabilization. This Leads To (i) Loss Of Intracellular Solutes (e.g., K+ And Amino Acids); (ii) Dissipation Of The Transmembrane Potential; (iii) Inhibition Of Respiration; (iv) A Reduction In ATP Pools; And (v) Inhibition Of DNA, RNA, And Protein Synthesis, Which Leads To Cell Death.
Drug Interaction of Gramicidin :Superficial Infections.
Side effects of Gramicidin :Irritation.


INTERACTIONS OF GRAMICIDIN


How Gramicidin will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Gramicidin will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Gramicidin

No Studies Found