Generic ( Glucagon )
|Typical use Of Glucagon :||Hypoglycaemia. Cardiogenic. Diagnosis Of Pheochromocytoma|
|Mechanism of action of Glucagon :||Glucagon Binds The Glucagon Receptor, A G Protein-coupled Receptor Located In The Plasma Membrane, Which Then Initiates A Dual Signaling Pathway Using Both Adenylate Cyclase Activation And Increased Intracellular Calcium. Adenylate Cyclase Manufactures CAMP (cyclic AMP), Which Activates Protein Kinase A (cAMP-dependent Protein Kinase). This Enzyme, In Turn, Activates Phosphorylase Kinase, Which, In Turn, Phosphorylates Glycogen Phosphorylase, Converting Into The Active Form Called Phosphorylase A. Phosphorylase A Is The Enzyme Responsible For The Release Of Glucose-1-phosphate From Glycogen Polymers.|
|Drug Interaction of Glucagon :||Glucagon Is Known To Interact With Other Drugs Like Insulin Glulisine, Warfarin (Na). Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.|
|Side effects of Glucagon :||Hypokalemia, Nausea And Vomiting, Hypersensitivity Reactions.|
INTERACTIONS OF GLUCAGON
How Glucagon will impact on Pregnancy ?Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.
How Glucagon will impact during lactation(breastfeeding) ?Safer: Drug Has Been Studied In Few Breastfeeding Women And The Evidence Shows That There Is No Increase In Side Effects In The Infants, Or The Possibility Of Harm To The Breastfed Infants Is Expected To Be Rare. Patients Should Follow The Advice Of The Doctor Regarding Its Use.
Medicine & Alcohol use and effect of GlucagonNo Studies Found