Medicine : Glosilex

Name:Glosilex
Type:Cream
Manufacturer:Aglowmed Drugs Pvt. Ltd.
Generic Use:Chlorhexidine Gluconate , Sulphadiazine
Composition:Chlorhexidine Gluconate(0.2%w/w) , Sulphadiazine(1%w/w)
Substitutes:silverex a ceam(240gm) , glosilex , silverex a ceam(240gm) , glosilex


Generic ( Chlorhexidine Gluconate )



Typical use Of Chlorhexidine Gluconate :Abrasion, Bladder Irrigation, Bleeding, Burns, Cuts, Gingivitis, Infected Cracked Skin, Minor Burns, Minor Scalds, Pleural And Peritoneal Irrigation, Skin Infections, Skin Lesions, Sunburn Blisters, Ulcers, Urethral Infection.
Mechanism of action of Chlorhexidine Gluconate :Chlorhexidine's Antimicrobial Effects Are Associated With The Attractions Between Chlorhexidine (cation) And Negatively Charged Bacterial Cells. After Chlorhexidine Is Absorpted Onto The Organism's Cell Wall, It Disrupts The Integrity Of The Cell Membrane And Causes The Leakage Of Intracellular Components Of The Organisms.
Drug Interaction of Chlorhexidine Gluconate :Chlorhexidine Is Known To Interact With Other Drugs Like Povidone-iodine. These Interactions Are Sometimes Beneficial And Sometimes May Pose Threats To Life. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Chlorhexidine Gluconate :Shortness Of Breadth, Hemolysis, Hypersensitivity Reactions, Photophobia, Slurred Speech, Allergic Skin Reactions, Nausea, Vomiting, Allergic Reactions, Photosensitivity, Skin Irritation, Skin Sensitization, Irritation Of Sensitive Tissues, Dermatitis, Taste Disturbances, Teeth Discoloration.

INTERACTIONS OF CHLORHEXIDINE GLUCONATE


How Chlorhexidine Gluconate will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Chlorhexidine Gluconate will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Chlorhexidine Gluconate

No Studies Found






Generic ( Sulphadiazine )



Typical use Of Sulphadiazine :Chancroid, GI Infections, Malaria, Nocardiosis, Pneumonia, Prevention Of Rheumatic Fever Recurrence, Respiratory Tract Infections, Superficial Infections, Toxoplasmosis, Urinary Tract Infection.
Mechanism of action of Sulphadiazine :Sulfadiazine Is A Competitive Inhibitor Of The Bacterial Enzyme Dihydropteroate Synthetase. This Enzyme Is Needed For The Proper Processing Of Para-aminobenzoic Acid (PABA) Which Is Essential For Folic Acid Synthesis. The Inhibited Reaction Is Necessary In These Organisms For The Synthesis Of Folic Acid.
Drug Interaction of Sulphadiazine :Sulphadiazine Is Known To Interact With Other Drugs Like Ascorbic Acid, Chlorpropamide, Methotrexate, Phenytoin (Na), Procaine, Pyrimethamine, Tolbutamide, Torasemide, Trimethoprim, Warfarin (Na). Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Sulphadiazine :Granulocytopenia, Nephrotic Syndrome, Serum Sickness Like Illness, Dizziness, Headache, Nausea, Vomiting, Rashes.

INTERACTIONS OF SULPHADIAZINE


How Sulphadiazine will impact on Pregnancy ?

Experiences Of Drug Use And Evidence From Studies In Pregnant Women Have Shown Risk To Fetus. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Sulphadiazine will impact during lactation(breastfeeding) ?

Possibly Unsafe: Evidence From Studies In Breastfeeding Women Show That There Is A Definite Risk Of Side Effects To The Breastfed Infants. However, Use Of The Drug In Breastfeeding Women Is Acceptable In Spite Of The Risk To The Infants, If The Drug Is Needed In A Life-threatening Situation Or For A Serious Disease For Which Safer Drugs Cannot Be Used Or Are Ineffective. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Sulphadiazine

No Studies Found