Medicine : Gliogen (250mg)

Name:Gliogen (250mg)
Manufacturer:Samarth Life Sciences
Generic Use:Temozolomide
Composition:Temozolomide(250 Mg)
Substitutes:tabze (250mg) , emzolam (250mg) , temolon (250mg) , glioz (250mg) , temodal (250mg) , emozolam (250mg) , gliogen (250mg)

Generic ( Temozolomide )

Typical use Of Temozolomide :Glioblastoma Multiforme, Metastatic Melanoma
Mechanism of action of Temozolomide :Temozolomide, A Triazene, Is An Inactive Prodrug. It Is Chemically Hydrolysed To 3-methyl-(triazen-1-yl) Imidazole-4-carboxamide (MTIC), The Active Metabolite Of Dacarbazine. The Cytotoxicity Of MTIC Is Believed To Be Due Alkylation Of DNA, Mainly At The O6 And N7 Positions Of Guanine.
Drug Interaction of Temozolomide :Temozolomide Is Known To Interact With Other Drugs Like Natalizumab, Trastuzumab. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Temozolomide :Nausea, Vomiting, Taste Perversion, Constipation, Diarrhoea, Abdominal Pain, Stomatitis, Anorexia, Headache, Fatigue, Convulsions, Dizziness, Memory Impairment, Impaired Concentration, Tremors, Blurred Vision, Hearing Impairment, Speech Disorder, Rash, Infection, Oral Candidiasis, Dyspnoea, Coughing, Neutropenia, Thrombocytopenia.


How Temozolomide will impact on Pregnancy ?

Experiences Of Drug Use And Evidence From Studies In Pregnant Women Have Shown Risk To Fetus. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Temozolomide will impact during lactation(breastfeeding) ?

Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.

Medicine & Alcohol use and effect of Temozolomide

No Studies Found