Medicine : Galvusmet (50/850)

Name:Galvusmet (50/850)
Manufacturer:Novartis Pharmaceuticals Ltd
Generic Use:Metformin , Vildagliptin
Composition:Metformin(850mg) , Vildagliptin(50mg)
Substitutes:jalra m 50/(850mg) , galvusmet (50/850) , galvus met(50mg / 850mg) , jalra m 50/(850mg) , galvusmet (50/850) , galvus met(50mg / 850mg)

Generic ( Metformin )

Typical use Of Metformin :Metformin Is Used In The Treatment Of Diabetes Mellitus, Insulin Resistance, And Obesity.
Mechanism of action of Metformin :The Exact Mechanism Of Action Of Metformin Is Not Clear But It Appears To Act By Decreasing Glucose Absorption From The Intestine, Decreasing Production Of Glucose From Proteins And Fats In Liver, And Enhancing Insulin Sensitivity In Muscle By Increasing Glucose Uptake And Utilization.
Drug Interaction of Metformin :Taking Metformin With Other Anti-diabetic Drugs May Lead To Excessive Lowering Of Bloodsugar. If You Go For An X-ray Or Scan, Do Not Take Metformin Before And At Least 48 Hours Afterwards. Metformin With Diuretics (furosemide), Anti-asthmatic Drugs Such As Salbutamol Or Terbutaline, Or Corticosteroids (prednisone) May Affect The Glucose Control. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Metformin :The Common Side Effects Are Urge To Vomit, Vomiting, Diarrhea, Abdominal Pain, Loss Of Appetite, Malabsorption Of Vitamin B12, Taste Disturbance, And Altered Liver Functions. Also, The Patient May Have The Side Effects Of Lactic Acidosis (symptoms Are Vomiting, Abdominal Pain With Muscle Cramps, Not Feeling Well With Severe Tiredness, And Difficulty In Breathing), And Skin Reactions Such As Redness Of Skin, Itching, Hives (pale Red, Raised, Itchy Bumps Of Skin).


How Metformin will impact on Pregnancy ?

The Drug Should Not Be Used By Pregnant Women. Experiences Of Drug Use And Evidence From Studies In Pregnant Women Have Shown High Risk To Fetus. The Risk Of Drug Use In Pregnant Women Outweighs The Benefit.

How Metformin will impact during lactation(breastfeeding) ?

Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.

Medicine & Alcohol use and effect of Metformin

No Studies Found

Generic ( Vildagliptin )

Typical use Of Vildagliptin :To Control High Blood Glucose In Type 2 Diabetes Mellitus
Mechanism of action of Vildagliptin :Vildagliptin Works By Increasing The Amount Of Two Incretin Hormones Found In The Body, Called Glucagon-like Peptide-1 (GLP-1) And Glucose-dependent Insulinotropic Peptide (GIP). Firstly, They Stimulate The Pancreas To Produce Insulin In Response To Increasing Levels Of Glucose In The Blood. GLP-1 Also Reduces The Production Of Glucagon (hormone That Normally Increases Glucose Production By The Liver). GLP-1 And GIP Are Normally Broken Down By An Enzyme In The Body Called Dipeptidyl Peptidase-4 (DPP-4). Vildagliptin Works By Binding To This Enzyme And Preventing It From Breaking Down GLP-1 And GIP And Thus Reducing The High Blood Glucose Level.
Drug Interaction of Vildagliptin :Vildagliptin May Interact With Thiazides (bendroflumethiazide, Hydrochlorothiazide) Or Other Diuretics, Corticosteroids, Thyroid Medicines, Medicines Affecting The Nervous System. Always Consult Your Doctor For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Vildagliptin :Rapid Swelling Of The Deep Layers Of Skin Around Eyes And Lips (angioedema), Inflammation Of Liver, Abnormal Liver Function Tests, And Inflammation Of The Pancreas. Other Common Side Effects Noted When Vildagliptin Is Taken Along With Other Antidiabetic Agents Include Chills, Headache, Tremors, Heartburn, Dizziness, Weakness, Fever, Urge To Vomit (nausea), Swelling Of Feet And Lower Legs, Excessive Sweating And Fall In Blood Glucose (hypoglycemia).


How Vildagliptin will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Vildagliptin will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Vildagliptin

No Studies Found