Medicine : Flabone

Name:Flabone
Type:Tablet
Manufacturer:Gufic Chem Pvt Ltd
Generic Use:Alfacalcidol , Calcium , Vitamin C
Composition:Alfacalcidol(0.25Mcg) , Calcium(1200Mg) , Vitamin C(50mg)
Substitutes:flabone , flabone , flabone


Generic ( Alfacalcidol )



Typical use Of Alfacalcidol :Managing Hypocalcemia In Patients Undergoing Dialysia For Chronic Renal Failure. Renal Osteodystrophy. Hypocalaemia And Hyperphosphataemia. Vitamin D Dependent Rickets, Renal Tubular Osteomalacia.
Mechanism of action of Alfacalcidol :Alfacalcidol Is A Precursor Of The Active Calcitriol. It Does Not Require Renal Hydroxylation But Requires 25-hydroxylation In The Liver For Conversion To Calcitriol.
Drug Interaction of Alfacalcidol :Thiazides May Increase The Risk Of Hypercalcaemia. Some Antiepileptics E.g. Carbamazepine, Phenobarbital, Phenytoin And Primidone May Increase Vitamin D Requirements.
Side effects of Alfacalcidol :Anorexia, Nausea, Vomiting, Diarrhoea.

INTERACTIONS OF ALFACALCIDOL


How Alfacalcidol will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Alfacalcidol will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Alfacalcidol

No Studies Found






Generic ( Calcium )



Typical use Of Calcium :Calcium Supplements Are Usually Used To Prevent Or Treat Low Blood Calcium Levels In People Who Do Not Get Enough Calcium From Their Food. The Amount Of Calcium Required Everyday Varies With Age And Gender. The Demand Is Generally Higher During Childhood, Pregnancy, Lactation And Postmenopausal Phase. Calcium Supplements Are Used To Treat Patients With Calcium Deficiency, Brittle Bones, Reduced Absorption Of Nutrients After Surgery Performedto Remove All Or Part Of The Stomach, Bone Softening And Bone Disease Due To Vitamin D Deficiency.
Mechanism of action of Calcium :Calcium Is Necessary For Normal Functioning Of Nerves, Cells, Muscle, And Bone. If There Is Not Enough Calcium In The Blood, Then The Body Will Take Calcium From Bones, Thereby Weakening Bones. On Administration Of Calcium Supplements, About One-third Of The Ingested Calcium Is Absorbed From The Small Intestine. Absorption Decreases With Age And May Be More Efficient When The Body Is Deficient In Calcium Or From Diets Deficient In Calcium. The Best-absorbed Form Of Calcium From A Pill Is A Calcium Salt Like Carbonate Or Phosphate. Calcium Gluconate And Calcium Lactate Are Absorbed Well By Pregnant Women. Elderly Population Absorb Calcium Lactate, Gluconate And Citrate Better Unless They Take Their Calcium Supplement With A Full Breakfast.
Drug Interaction of Calcium :Care Should Be Taken While Administering Calcium In Patients Receiving Vitamin Or Mineral Preparations As They Contain Additional Calcium. Calcium Increases The Effects Of Digoxin On The Heart. It Is Known To Reduce The Absorption Of Tetracycline Drugs. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Calcium :Constipation

INTERACTIONS OF CALCIUM


How Calcium will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Calcium will impact during lactation(breastfeeding) ?

Safest: Evidence From Clinical Studies Has Shown That This Drug When Taken By Breastfeeding Mothers Has Not Shown Any Major Side Effects In Infants. The Possibility Of Harm To The Breastfed Infants Is Expected To Be Rare Or The Drug Does Not Reach The Infant Through Breast Milk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Calcium

No Studies Found






Generic ( Vitamin C )



Typical use Of Vitamin C :Treatment Of Scurvy. Adjuvent Therapy In Common Cold, Asthma, Cancer, Atherosclerosis.Thalassaemia. Metabolic Disorders (tyrosinaemia Type III, Transient Tyrosinaemia Of The Newborn, Glutathione Synthase Deficiency, Hawkinsinuria).
Mechanism of action of Vitamin C :Ascorbic Acid Is A Functional And Principal In Vivo Form Of Vitamin C, An Essential Water-soluble Vitamin Which Is Fundamental In The Synthesis Of Collagen And Intercellular Materials.
Drug Interaction of Vitamin C :Deferroxamine, Hormonal Contraceptives, Flufenazine, Warfarin, Elemental Iron.
Side effects of Vitamin C :Diarrhea, GI Disturbances. May Cause Acidification Of The Urine.

INTERACTIONS OF VITAMIN C


How Vitamin C will impact on Pregnancy ?

There Is Sufficient Evidence To Suggest That There Is No Risk To The Fetus In The First Trimester (12 Weeks) Of Pregnancy And There Is No Evidence Of Risk In Later Trimesters. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Vitamin C will impact during lactation(breastfeeding) ?

Safest: Evidence From Clinical Studies Has Shown That This Drug When Taken By Breastfeeding Mothers Has Not Shown Any Major Side Effects In Infants. The Possibility Of Harm To The Breastfed Infants Is Expected To Be Rare Or The Drug Does Not Reach The Infant Through Breast Milk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Vitamin C

No Studies Found