Medicine : Esblanem (1gm)

Name:Esblanem (1gm)
Manufacturer:Glaxo Smithkline Pharmaceuticals Ltd
Generic Use:Meropenem
Substitutes:meroplan (1gm) , ameropem (1g) , micropenam (1gm) , esblanem (1gm) , meropan (1gm) , paranem (1gm) , merocrit (1gm) , wopenem (1000mg) , icu bac(1gm)

Generic ( Meropenem )

Typical use Of Meropenem :Nosocomial Infections Like Septicaemia, Febrile Neutropenia, Intraabdominal And Pelvic Infections, Etc. Caused By Cephalosporin-resistant Bacteria. For P Aeruginosa Infections, It Should Be Combined With An Aminoglycoside.
Mechanism of action of Meropenem :The Bactericidal Activity Of Meropenem Results From The Inhibition Of Cell Wall Synthesis. Meropenem Readily Penetrates The Cell Wall Of Most Gram-positive And Gram-negative Bacteria To Reach Penicillin-binding- Protein (PBP) Targets. Its Strongest Affinities Are Toward PBPs 2, 3 And 4 Of Escherichia Coli And Pseudomonas Aeruginosa; And PBPs 1, 2 And 4 Of Staphylococcus Aureus.
Drug Interaction of Meropenem :Meropenem Is Known To Interact With Other Drugs Like Probenecid, Sodium Valproate. These Interactions Are Sometimes Beneficial And Sometimes May Pose Threats To Life. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Meropenem :Pseudomembranous Colitis, Thrombocytopenia, Eosinophilia, Seizures, Headache, Nausea, Vomiting, Diarrhea, Constipation, Abdominal Pain, Rashes, Urticaria, Pruritus, Elevation Of Liver Enzymes.


How Meropenem will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Meropenem will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Meropenem

No Studies Found