Medicine : Epicortmk

Name:Epicortmk
Type:Cream
Manufacturer:Shrey Nutraceuticals & Herbals Pvt Ltd
Generic Use:Betamethasone , Salicylic Acid , Urea
Composition:Betamethasone(0.05%W/V) , Salicylic Acid(3%w/v) , Urea(10%W/V)
Substitutes:epicortmk , epicortmk , epicortmk


Generic ( Betamethasone )



Typical use Of Betamethasone :Replacement Therapy: Adrenal Insufficiency. Adrenogenital Syndrome.Nonendocrine Diseases: Rheumatoid Arthirits. Osteoarthritis, Acute Gouty Arthirits. Collagen Diseases E.g. Systemic Lupus Erythematosus, Polyarteritis Nodosa, Dermatomyositis, Nephritic Syndrome, Glomerulonephritis And Related Diseases.Severe Allergic Reactions E.g. Anaphylaxis, Angioneurotic Edema, Urticaria And Serum Sickness And Related Diseases.Autoimmune Diseases E.g. Haemolytic Anaemia, Idiopathic Thrombocytopenic Purpura, Active Chronic Hepatitis And Related Diseases.Other Lung Diseases E.g. Pulmonary Edema, Accelerate Lung Maturation And Surfactant Production In The Foetus And Prevent Respiratory Distress Syndrome At Birth.Infective Diseases E.g. Severe Forms Of Tuberculosis, Severe Lepra Reaction, Certain Forms Of Bacterial Meningitis And Pneumocystis Carinii Pneumonia With Hypoxia In AIDS Patients Along With Proper Antibiotic Cover.Eye Diseases E.g. Inflammatory Ocular Diseases, Allergic Conjunctivitis, Iritis, Iridocyclitis, Keratitis, Retinitis, Optic Neuritis, Uveitis.Skin Diseases E.g. Eczematous Skin Diseases. Pemphigus Vulgaris, Exfoliative Dermatitis, Stevens Johnson Syndrome.Intestinal Diseases E.g. Ulcerative Colitis, Crohns Disease, Coeliac Disease Are Chronic Inflammatory Intestinal Diseases.Cerebral Edema.Malignancies E.g. Acute Lymphatic Leukaemia, Hodgkins And Other Lymphomas. Hormone Responsive Breast Carcinoma.Organ Transplantation And Skin Allograft.Septic Shock.Thyroid Storm.
Mechanism of action of Betamethasone :Betamethasone Is A Glucocorticoid Receptor Agonist. This Leads To Changes In Genetic Expression Once This Complex Binds To The GRE. The Antiinflammatory Actions Of Corticosteroids Are Thought To Involve Lipocortins, Phospholipase A2 Inhibitory Proteins Which, Through Inhibits Arachidonic Acid, Control The Biosynthesis Of Prostaglandins And Leukotrienes.
Drug Interaction of Betamethasone :Betamethasone Is Known To Interact With Other Drugs Like Amphotericin B, Carbamazepine, Lofexidine, Metyrosine, Oxandrolone, Perindopril, Phenytoin (Na), Rifampicin. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Betamethasone :Atrophy, Steroid Purpura, Steroid Purpura, Skin Fragility, Angioedema, Perioral Dermatitis, Vertigo, Headache, Diarrhea, Fever, Anxiety, Constipation, Abdominal Pain, Sweating, Erythema, Hypotension, Arthralgia, Acne, Hypersensitivity Reactions, Menstrual Irregularity, Cataract, Hypertrichosis, Pigmentation, Superficial Blood Vessels Dilatation, Local Hypopigmentation.

INTERACTIONS OF BETAMETHASONE


How Betamethasone will impact on Pregnancy ?

Experiences Of Drug Use And Evidence From Studies In Pregnant Women Have Shown Risk To Fetus. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Betamethasone will impact during lactation(breastfeeding) ?

Possibly Unsafe: Evidence From Studies In Breastfeeding Women Show That There Is A Definite Risk Of Side Effects To The Breastfed Infants. However, Use Of The Drug In Breastfeeding Women Is Acceptable In Spite Of The Risk To The Infants, If The Drug Is Needed In A Life-threatening Situation Or For A Serious Disease For Which Safer Drugs Cannot Be Used Or Are Ineffective. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Betamethasone

No Studies Found






Generic ( Salicylic Acid )



Typical use Of Salicylic Acid :Hyperkeratotic And Scaling Skin Conditions, Acne, Warts And Calluses.
Mechanism of action of Salicylic Acid :Salicylic Acid Has A Potent Keratolytic Action And A Slight Antiseptic Action When Applied Topically. It Softens And Destroys The Stratum Corneum By Increasing Endogenous Hydration Which Causes The Horny Layer Of The Skin To Swell, Soften, And Then Desquamate. At High Concentrations, Salicylic Acid Has A Caustic Effect. It Also Possesses Weak Antifungal And Antibacterial Activity.
Drug Interaction of Salicylic Acid :Hyperkeratotic And Scaling Skin Conditions, Acne, Warts And Calluses.
Side effects of Salicylic Acid :Irritation, Sensitivity, Excessive Drying; Systemic Effects On Prolonged Use.

INTERACTIONS OF SALICYLIC ACID


How Salicylic Acid will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Salicylic Acid will impact during lactation(breastfeeding) ?

Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.

Medicine & Alcohol use and effect of Salicylic Acid

No Studies Found






Generic ( Urea )



Typical use Of Urea :Dry Skin, Eczema, Onychomycoses, Pruritus, Psoriasis, Skin Ulceration, Slack Hairy Tounge.
Mechanism of action of Urea :Urea Is An Osmotic Diuretic Similar To Mannitol But More Irritant. It Induces Diuresis By Increasing Osmotic Pressure Ofthe Glomerular Filtrate And Increasing Excretion Of Sodium, Potassium And Chloride Ions. Its Osmotic Effect Also Draws Water From Cells E.g. Brain, CSF And Anterior Chamber Of The Eye, Thereby Decreasing Intracranial Or Intraocularpressure. Applied Topically, Urea Promotes Hydration Of Keratin And Mild Keratolysis In Dry Skin. It Increases Water Uptake By The Stratum Corneum And Has An Antipruritic Effect.
Drug Interaction of Urea :Urea Is Known To Interact With Other Drugs Like Lypressin, Vasopressin. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Urea :Irritation, Burning, Skin Eruptions.

INTERACTIONS OF UREA


How Urea will impact on Pregnancy ?

There Are No Studies Available Regarding Its Use During Pregnancy. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Urea will impact during lactation(breastfeeding) ?

There Are No Studies Available Regarding Its Use During Lactation. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Urea

No Studies Found