Medicine : Entrofuran M Tab

Name:Entrofuran M Tab
Type:Tablet
Manufacturer:Deys Medical Stores Mfg Ltd (dey's Medical)
Generic Use:Furazolidone , Metronidazole
Composition:Furazolidone(100Mg) , Metronidazole(300mg)
Substitutes:dependal , dependal m tab , entrofuran m tab , dependal , dependal m tab , entrofuran m tab


Generic ( Furazolidone )



Typical use Of Furazolidone : Bacterial Enteritis. Food Poisoning. Diarrhoeas, Bacillary Dysentery, Giardiasis.
Mechanism of action of Furazolidone :Furazolidone And Its Related Free Radical Products Are Believed To Bind DNA And Induce Cross-links. Bacterial DNA Is Particularly Susceptible To This Drug Leading To High Levels Of Mutations (transitions And Transversions) In The Bacterial Chromosome.
Drug Interaction of Furazolidone :Furazolidone Is Known To Interact With Other Drugs Like Adrenaline, Albuterol, Alcohol, Amitriptyline (HCl), Carbamazepine, Dopamine (HCl), Doxapram, Ephedrine, Levodopa, Maprotiline (HCl), Metaraminol, Methylamphetamine, Methyldopa.
Side effects of Furazolidone :Headache, Nausea, Vomiting, Fever, Urticaria, Redness, Malaise, Hypotension, Arthralgia.

INTERACTIONS OF FURAZOLIDONE


How Furazolidone will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Furazolidone will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Furazolidone

No Studies Found






Generic ( Metronidazole )



Typical use Of Metronidazole :Amoebiasis, Giardiasis, Trichomonas Vaginitis, Anaerobic Infections, Ulcerative Gingivitis.Eradication Of H.pylori Associated With Peptic Ulcer Disease.Antibiotic-associated Coulitis. Trichomoniasis, Balantidiasis, Blastocyatis Hominis Infection. Adjunct To Treatment Of Chronic Periodontal Infections. Rosacea.
Mechanism of action of Metronidazole :Metronidazole Is Converted To Reduction Products That Interact With DNA To Cause Destruction Of Helical DNA Structure And Strand Leading To A Protein Synthesis Inhibition And Cell Death In Susceptible Organisms. It Is Effective Against A Wide Range Of Organisms Including E. Histolytica, T. Vaginalis, Giardia, Anaerobes E.g. Bacterioides Sp, Fusobacterium Sp, Clostridium Sp.
Drug Interaction of Metronidazole :Acute Psychoses Or Confusion With Disulfiram. It Has Synergistic Effect With Other Antimicrobials. Effects Reduced With Phenobarbital Or Phenytoin. Disulfiram-like Reaction With Alcohol. Increased Risk Of Adverse Effects Of Coumarin Anticoagulants, Phenytoin, Lithium, Ciclosporin, Fluorouracil. Increased Risk Of Neurological Effects With Cimetidine.
Side effects of Metronidazole :GI Disturbances E.g. Nausea, Unpleasant Metallic Taste, Vomiting, Diarrhoea Or Constipation. Furred Tongue, Glossitis, And Stomatitis Due To Overgrowth Of Candida. Rarely, Antibiotic-associated Colitis. Weakness, Dizziness, Ataxia, Headache, Drowsiness, Insomnia, Changes In Mood Or Mental State. Numbness Or Tingling In The Extremities, Epileptiform Seizures (high Doses Or Prolonged Treatment). Transient Leucopenia And Thrombocytopenia. Hypersensitivity Reactions. Anaphylaxis.

INTERACTIONS OF METRONIDAZOLE


How Metronidazole will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Metronidazole will impact during lactation(breastfeeding) ?

Safer: Drug Has Been Studied In Few Breastfeeding Women And The Evidence Shows That There Is No Increase In Side Effects In The Infants, Or The Possibility Of Harm To The Breastfed Infants Is Expected To Be Rare. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Metronidazole

No Studies Found