Medicine : Endonac P(10s)

Name:Endonac P(10s)
Type:Tablet
Manufacturer:Endocard India Pvt Ltd
Generic Use:Aceclofenac , Paracetamol
Composition:Aceclofenac(100 Mg) , Paracetamol(325 Mg)
Substitutes:aceclodin sp tab , aceparon tab , maxzen p , nu flexlor tab(10s) , acecloren tab , delupa p tab , endocef dry syp(30ml) , endonac p(10s) , atisac p , atisac sp , accemol tab , axofen plus tab , acekay plus tab , aceclodin sp tab , aceparon tab , maxzen p , nu flexlor tab(10s) , acecloren tab , delupa p tab , endocef dry syp(30ml) , endonac p(10s) , atisac p , atisac sp , accemol tab , axofen plus tab , acekay plus tab


Generic ( Aceclofenac )



Typical use Of Aceclofenac :Aceclofenac Is Used To Relieve Pain And Inflammation Of Joints And Vertebrae In Conditions Such As Osteoarthritis, Rheumatoid Arthritis And Ankylosing Spondylitis.
Mechanism of action of Aceclofenac :Aceclofenac Works By Blocking The Effect Of Chemicals Called Cyclooxygenase Enzymes. These Enzymes Help To Make Other Chemicals In The Body, Called Prostaglandins. Prostaglandins Are Produced At Sites Of Injury Or Damage, And Cause Pain And Swelling. By Blocking The Effect Of Cyclooxygenase Enzymes, Production Of Prostaglandins Are Reduced, Thus, Pain And Swelling Are Eased. 
Drug Interaction of Aceclofenac :Aceclofenac May Increase Concentrations Of Lithium, Digoxin And Methotrexate In The Blood, Increase The Activity Of Anticoagulants (warfarin), Reduce The Activity Of Diuretics (furosemide) And Anti-hypertensives, Cause Increased Toxicity In Kidney (cyclosporine). Interaction With Quinolone Antibiotics (ciprofloxacin, Levofloxacin), Anti-diabetic Drugs, Pain Killers (aspirin, Ibuprofen), Or Corticosteroids Can Cause Adverse Effects. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Aceclofenac :The Most Common Side Effects Are Gastrointestinal In Nature Including Ulcers In The Mouth, Stomach And Small Intestine, Urge To Vomit, Vomiting, Diarrhea, Constipation, Excessive Passage Of Wing Or Gas, Indigestion, Abdominal Pain, Blood In Stools. Other Common Side Effects Are Swelling Of Part Or Whole Of The Body, Increased Blood Pressure, Heart Failure, And Severe Allergic Reactions.

INTERACTIONS OF ACECLOFENAC


How Aceclofenac will impact on Pregnancy ?

Experiences Of Drug Use And Evidence From Studies In Pregnant Women Have Shown Risk To Fetus. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Aceclofenac will impact during lactation(breastfeeding) ?

Possibly Unsafe: Evidence From Studies In Breastfeeding Women Show That There Is A Definite Risk Of Side Effects To The Breastfed Infants. However, Use Of The Drug In Breastfeeding Women Is Acceptable In Spite Of The Risk To The Infants, If The Drug Is Needed In A Life-threatening Situation Or For A Serious Disease For Which Safer Drugs Cannot Be Used Or Are Ineffective. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Aceclofenac

No Studies Found






Generic ( Paracetamol )



Typical use Of Paracetamol :Paracetamol Is Used For The Relief Of Mild To Moderate Pain In Conditions Such As Headache (including Migraine), Toothache, Ear Pain, Joint Pain, Pain Of Menstruation, Fever, Feverish Colds, And Flu.
Mechanism of action of Paracetamol :Paracetamol Is Categorized As An Analgesic (painkiller) And Antipyretic (fever Reducing) Drug. Paracetamol Reduces Pain By Increasing The Pain Threshold. It Reduces Fever By Acting On The Temperature-regulating Region Of Brain, Resulting In Increased Blood Flow Across The Skin, Sweating And Heat Loss.
Drug Interaction of Paracetamol :Cholestyramine, Metoclopramide And Domperidone May Alter The Effects Of Paracetamol. Use Of Paracetamol With Warfarin May Increase The Risk Of Bleeding. Paracetamol May Increase The Effects Of Chloramphenicol. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Paracetamol :Side Effects Of Paracetamol Are Usually Rare, And Include Allergic Reactions Such As Shortness Of Breath, Abnormalities Of Blood Cells, Skin Reddening, Blisters Or Rash, Swollen Facial Features, Or A Runny Nose. Overdose (more Than 4 G In Adults And More Than 2 G In Children) May Cause Severe Liver Damage.

INTERACTIONS OF PARACETAMOL


How Paracetamol will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Paracetamol will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Paracetamol

No Studies Found