Medicine : Enace D(2.5mg)

Name:Enace D(2.5mg)
Manufacturer:Abbott India Ltd
Generic Use:Enalapril , Hydrochlorothiazide
Composition:Enalapril(2.5 Mg) , Hydrochlorothiazide(12.5 Mg)
Substitutes:enace d(2.5mg) , enace d(2.5mg)

Generic ( Enalapril )

Typical use Of Enalapril :All Grades Of Essential Hypertension And Renovascular Hypertension. Adjunct In Congestive Heart Failure.
Mechanism of action of Enalapril :Enalapril Is De-esterified Into The Active Enalaprilat Resulting In Potent Inhibition Of ACE Thus Leading To Reduced Levels Of Angiotensin II And Aldosterone. Clinically, BP Is Reduced, Salt And Water Retention Is Corrected. Ventricular Hypertrophy Is Reversed. Renal Blood Flow Is Increased But In Patients With Renal Impairment There May Be Oliguria Or Acute Renal Failure.
Drug Interaction of Enalapril :Patients Receiving Diuretics May Experience Excessive Reduction In Blood Pressure When Enalapril Is Started. Close Supervision For At Least 2 Hours After The Start Of Enalapril And Until Blood Pressure Is Stable Is Recommended If The Diuretic Cannot Be Stopped. Enalapril May Increase Potassium Levels (hyperkalemia) In Blood. Therefore, There Is An Increased Risk Of Hyperkalemia When Enalapril Is Given With Potassium Supplements Or Drugs That Increase Potassium Levels (for Example, Spironolactone [Aldactone]). There Have Been Reports Of Increased Lithium (Eskalith, Lithobid) Levels When Lithium Is Used In Combination With ACE Inhibitors. The Reason For This Interaction Is Not Known, But The Increased Levels May Lead To Toxicity From Lithium. There Have Been Reports That Aspirin And Other Nonsteroidal Anti-inflammatory Drugs (NSAIDs) Such As Ibuprofen (Advil, Children's Advil/Motrin, Medipren, Motrin, Nuprin, PediaCare Fever, Etc.), Indomethacin(Indocin, Indocin-SR), And Naproxen (Anaprox, Naprelan, Naprosyn, Aleve) May Reduce The Effects Of ACE Inhibitors.
Side effects of Enalapril :Initial Hypotension May Be Severe And Prolonged. Dizziness, Headache, Fatigue, Persistent Dry Cough, Abnormal Taste, Lassitude, Rash, Neutropenia, Renal Impairment Or Failure.


How Enalapril will impact on Pregnancy ?

Experiences Of Drug Use And Evidence From Studies In Pregnant Women Have Shown Risk To Fetus. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Enalapril will impact during lactation(breastfeeding) ?

Possibly Unsafe: Evidence From Studies In Breastfeeding Women Show That There Is A Definite Risk Of Side Effects To The Breastfed Infants. However, Use Of The Drug In Breastfeeding Women Is Acceptable In Spite Of The Risk To The Infants, If The Drug Is Needed In A Life-threatening Situation Or For A Serious Disease For Which Safer Drugs Cannot Be Used Or Are Ineffective. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Enalapril

No Studies Found

Generic ( Hydrochlorothiazide )

Typical use Of Hydrochlorothiazide :Hydrochlorothiazide Is Used For The Treatment Of High Blood Pressure And Swelling Of The Body Due To Heart, Liver Or Renal Diseases And Corticosteroid Or Estrogen Therapy.
Mechanism of action of Hydrochlorothiazide :Hydrochlorothiazide Belongs To The Group Of Medicines Called Diuretics Which Increase The Urine Output. It Decreases Blood Pressure Together With Other Drugs (angiotensin Convertase Enzyme Inhibitors) That Reduce The Levels Of A Substance Called Angiotensin II.
Drug Interaction of Hydrochlorothiazide :Hydrochlorothiazide May Interact With Other Drugs Including Aspirin, Ibuprofen, Tubocurarine, Lithium Containing Drugs, Digitalis Glycosides, Nitrates Or Vasodilators, Cholestyramine,colestipol, Alcohol, Narcotics, And Corticosteroids. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Hydrochlorothiazide :Dizziness , Headache, Tiredness, Weakness, Sleepiness Or Sleeplessness, Diarrhea, Indigestion, Mild Stomach Pain, Urge To Vomit, Vomiting, Painful Muscles, Muscle Weakness, Back Pain, High Levels Of Uric Acid In The Blood Causing Swollen And Painful Joints, Nose Or Throat Infections, Nasal Stuffiness And/or Runny Nose.


How Hydrochlorothiazide will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Hydrochlorothiazide will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Hydrochlorothiazide

No Studies Found