Medicine : Duzela M(30)

Name:Duzela M(30)
Type:Capsule
Manufacturer:Sun Pharmaceutical Industries Ltd
Generic Use:Duloxetine , Mecobalamin
Composition:Duloxetine(30 Mg) , Mecobalamin(1.5 Mg)
Substitutes:duzela m(30) , duzela m(30)


Generic ( Duloxetine )



Typical use Of Duloxetine :Acute Lymphocytic Leukemia, Moderate To Severe Stress Urinary Incontinence In Women.
Mechanism of action of Duloxetine :Duloxetine Is A Potent Inhibitor Of Neuronal Serotonin And Norepinephrine Reuptake And A Less Potent Inhibitor Of Dopamine Reuptake. The Antidepressant And Pain Inhibitory Actions Of Duloxetine Are Believed To Be Related To Its Potentiation Of Serotonergic And Noradrenergic Activity In The CNS. Potentiation Of Serotonin And Norepinephrine Activity In The Spinal Cord, Which Increases Urethral Closure Forces And Thereby Reduces Involuntary Urine Loss.
Drug Interaction of Duloxetine :Duloxetine Hydrochloride Is Known To Interact With Other Drugs Like Oxymorphone. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Duloxetine :Weakness, Thirst, Fatigue, Nausea, Vomiting, Diarrhea, Constipation, Insomnia, Sweating, Blurred Vision, Pruritus, Lethargy, Dyspepsia, Sexual Dysfunction, Decrease In Libido.

INTERACTIONS OF DULOXETINE


How Duloxetine will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Duloxetine will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Duloxetine

No Studies Found






Generic ( Mecobalamin )



Typical use Of Mecobalamin :To Treat Low Hemoglobin Or Red Blood Cells (pernicious And Megaloblastic Anemia), Loss Of Sensation And Pain In Extremities (neuropathy). Also Used As Adjunct Therapy In Rare Conditions That Involves Severe Muscle Tightness And Decrease In Muscle Mass (amyotrophic Lateral Sclerosis).
Mechanism of action of Mecobalamin :Mecobalamin (active Form Of Vitamin B12) Assists Important Enzymes Involved In Energy Production Form Fats And Proteins And Synthesis Of Haemoglobin. It Is Known To Increase Production And Development Of Red Blood Cells By The Bone Marrow. It Assists Enzyme Methionine Synthase Which Is Involved In Breakdown Of Homocysteine Thereby Reducing Its Level.
Drug Interaction of Mecobalamin :Omeprazole, Lansoprazole, Cimetidine, Famotidine, Ranitidine, Neomycin, Colchicine, Chloramphenicol Reduce Blood Levels Of Mecobalamine. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Mecobalamin :It Is Usually Safe When Taken Orally. Loss Of Appetite, Nausea, Vomiting, Diarrhea, Allergic Reactions (skin Rashes), Itching And Other Injection Site Related Side Effects (pain And Blood Clots) May Occur.

INTERACTIONS OF MECOBALAMIN


How Mecobalamin will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Mecobalamin will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Mecobalamin

No Studies Found