Medicine : Donep M Forte Tab

Name:Donep M Forte Tab
Type:Tablet
Manufacturer:Alkem Laboratories Ltd
Generic Use:Donepezil Hydrochloride , Memantine
Composition:Donepezil Hydrochloride(10 Mg) , Memantine(10 Mg)
Substitutes:donep m forte tab , donep m forte tab


Generic ( Donepezil Hydrochloride )



Typical use Of Donepezil Hydrochloride :Induction Of General Anaesthesia, Mild To Moderately Severe Dementia In Alzheimer's Disease.
Mechanism of action of Donepezil Hydrochloride :Donepezil Produces Reversible Inhibition Of Cholinesterases (eg. Acetylcholinesterase), Which Prevents The Hydrolysis Of Acetycholine, And Leads To An Increased Concentration Of Acetylcholine At Cholinergic Synapses.
Drug Interaction of Donepezil Hydrochloride :Donepezil Is Known To Interact With Other Drugs Like Acepromazine, Aceprometazine, Amantadine, Brompheniramine, Chlorpheniramine, Chlorpromazine, Desipramine, Dicyclomine, Ethopropazine, Orphenadrine, Perphenazine, Prochlorperazine, Trimeprazine, Tripelennamine. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Donepezil Hydrochloride :Dizziness, Headache, Fatigue, Anorexia, Diarrhea, Insomnia, Rashes, Confusion, Pruritus, Hallucination, Psychiatric Disturbance, Urinary Incontinence, Nausea And Vomiting, Muscle Cramps, Syncope.

INTERACTIONS OF DONEPEZIL HYDROCHLORIDE


How Donepezil Hydrochloride will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Donepezil Hydrochloride will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Donepezil Hydrochloride

No Studies Found






Generic ( Memantine )



Typical use Of Memantine :Induction And Maintenance Of Anaesthesia.
Mechanism of action of Memantine :Memantine Binds More Effectively Than Mg2+ Ions At The NMDA Receptor, And Thereby Effectively Blocks This Prolonged Influx Of Ca2+ Ions Through The NMDA Channel Whilst Preserving The Transient Physiological Activation Of The Channels By Higher Concentrations Of Synaptically Released Glutamate. Thus Memantine Protects Against Chronically Elevated Concentrations Of Glutamate. Glutamate May Contribute To The Pathogenesis Of Alzheimer's Disease By Overstimulating Various Glutamate Receptors Resulting In Excitotoxicity And Neuronal Cell Death.
Drug Interaction of Memantine :Memantine Is Known To Interact With Other Drugs Like Apomorphine, Pergolide. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Memantine :Dizziness, Tiredness, Headache, Vomiting, Anxiety, Confusion, Hallucination, Cystitis, Hypertonia.

INTERACTIONS OF MEMANTINE


How Memantine will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Memantine will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Memantine

No Studies Found