Medicine : Doloforce Plus Tab

Name:Doloforce Plus Tab
Type:Tablet
Manufacturer:Mankind Pharma
Generic Use:Paracetamol , Piroxicam
Composition:Paracetamol(325 Mg) , Piroxicam(20 Mg)
Substitutes:doloforce plus tab , doloforce plus tab


Generic ( Paracetamol )



Typical use Of Paracetamol :Paracetamol Is Used For The Relief Of Mild To Moderate Pain In Conditions Such As Headache (including Migraine), Toothache, Ear Pain, Joint Pain, Pain Of Menstruation, Fever, Feverish Colds, And Flu.
Mechanism of action of Paracetamol :Paracetamol Is Categorized As An Analgesic (painkiller) And Antipyretic (fever Reducing) Drug. Paracetamol Reduces Pain By Increasing The Pain Threshold. It Reduces Fever By Acting On The Temperature-regulating Region Of Brain, Resulting In Increased Blood Flow Across The Skin, Sweating And Heat Loss.
Drug Interaction of Paracetamol :Cholestyramine, Metoclopramide And Domperidone May Alter The Effects Of Paracetamol. Use Of Paracetamol With Warfarin May Increase The Risk Of Bleeding. Paracetamol May Increase The Effects Of Chloramphenicol. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Paracetamol :Side Effects Of Paracetamol Are Usually Rare, And Include Allergic Reactions Such As Shortness Of Breath, Abnormalities Of Blood Cells, Skin Reddening, Blisters Or Rash, Swollen Facial Features, Or A Runny Nose. Overdose (more Than 4 G In Adults And More Than 2 G In Children) May Cause Severe Liver Damage.

INTERACTIONS OF PARACETAMOL


How Paracetamol will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Paracetamol will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Paracetamol

No Studies Found






Generic ( Piroxicam )



Typical use Of Piroxicam :Acute Gout, Acute Spasm And Spasm In Diagnostic Procedures, Ankylosing Spondylitis, Benign Gastric And Duodenal Ulceration, Duodenal Ulceration, Gout, Juvenile Chronic Arthritis, Musculoskeletal Disorders, Nausea And Vomiting (palliative Care), Osteoarthritis, Pain, Resistant Oedema, Rheumatoid Arthritis.
Mechanism of action of Piroxicam :Piroxicam Is A NSAID, Belonging To The Oxicam Group. It Inhibits Prostaglandin Synthesis, Reduces Fever By Acting On The Heat-regulating Center Of The Hypothalamus, Inhibits Platelet-aggregating Substance Thromboxane A2 And Reduces Pain Receptor Sensitivity. It Also Exerts Anti-inflammatory Effect By Lysosomal Stabilisation, Kinin And Leukotriene Production, Alteration Of Chemotactic Factors And Neutrophil Activation Inhibition.
Drug Interaction of Piroxicam :Ncreased Risk Of Hyperkalaemia When Used With ACE Inhibitors And Potassium-sparing Diuretics.
Side effects of Piroxicam :Dizziness, Headache, Palpitation, Insomnia, Confusion, VertigoX, Hearing Loss, Mood Swings, Paresthesias, Hypoglycemia.

INTERACTIONS OF PIROXICAM


How Piroxicam will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Piroxicam will impact during lactation(breastfeeding) ?

Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.

Medicine & Alcohol use and effect of Piroxicam

No Studies Found