Medicine : Dolocaine Cream(5gm)

Name:Dolocaine Cream(5gm)
Type:Cream
Manufacturer:Cadila Pharmaceuticals Ltd
Generic Use:Lidocaine , Prilocaine
Composition:Lidocaine(25 Mg) , Prilocaine(25 Mg)
Substitutes:dolocaine cream(5gm) , dolocaine cream(5gm)


Generic ( Lidocaine )


Typical use Of Lidocaine :Information Not Available.
Mechanism of action of Lidocaine :Lidocaine Stabilizes The Neuronal Membrane By Inhibiting The Ionic Fluxes Required For The Initiation And Conduction Of Impulses Thereby Effecting Local Anesthetic Action. Lidocaine Alters Signal Conduction In Neurons By Blocking The Fast Voltage Gated Sodium (Na+) Channels In The Neuronal Cell Membrane That Are Responsible For Signal Propagation. With Sufficient Blockage The Membrane Of The Postsynaptic Neuron Will Not Depolarize And Will Thus Fail To Transmit An Action Potential. This Creates The Anaesthetic Effect By Not Merely Preventing Pain Signals From Propagating To The Brain But By Aborting Their Birth In The First Place.
Drug Interaction of Lidocaine :Lignocaine Is Known To Interact With Other Drugs Like Alcuronium (Cl), Amphotericin B, Amprenavir, Atracurium (Besylate), Cimetidine (HCl), Edrophonium (Cl), Enflurane, Fosphenytoin, Halothane, Nadolol, Oxprenolol (HCl), Pentazocine, Propafenone (HCl). Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Lidocaine :Allergy, Hypotension, Bronchospasm, Coma, Seizures, Hypertension, Tissue Necrosis, Angina, Sinus Bradycardia, Respiratory Depression, Blurred Vision, Tremors, Respiratory Depression, Bradycardia, Convulsions, Hypersensitivity, Cardiac Arrest, CNS Toxicity, Dizziness, Headache, Drowsiness, Nausea, Vomiting, Anxiety, Restlessness, Palpitation, Nervousness, Tinnitus, Abdominal Pain, Confusion.

INTERACTIONS OF LIDOCAINE

How Lidocaine will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Lidocaine will impact during lactation(breastfeeding) ?

Possibly Unsafe: Evidence From Studies In Breastfeeding Women Show That There Is A Definite Risk Of Side Effects To The Breastfed Infants. However, Use Of The Drug In Breastfeeding Women Is Acceptable In Spite Of The Risk To The Infants, If The Drug Is Needed In A Life-threatening Situation Or For A Serious Disease For Which Safer Drugs Cannot Be Used Or Are Ineffective. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Lidocaine

No Studies Found





Generic ( Prilocaine )


Typical use Of Prilocaine :Local Anaesthetic.Injectable Form Is Used In DentIstry And Intravenous Regional Anaesthesia.
Mechanism of action of Prilocaine :Prilocaine Is A Local Anaesthetic Of The Amide Group. It Has Similar Anesth Potency To Lignocaine But It Has Slower Onset Of Action, Less Vasodilator Activity And A Slightly Longer Duration Of Action; It Is Also Less Toxic.
Drug Interaction of Prilocaine :Sulfonamides, Antimalarials, Certain Nitric Compounds May Potentiate Methemoglobinemia.
Side effects of Prilocaine :Vertigo, Nausea, Hypersensitivity Reactions, Nystagmus.

INTERACTIONS OF PRILOCAINE

How Prilocaine will impact on Pregnancy ?

Experiences Of Drug Use And Evidence From Studies In Pregnant Women Have Shown Risk To Fetus. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Prilocaine will impact during lactation(breastfeeding) ?

Possibly Unsafe: Evidence From Studies In Breastfeeding Women Show That There Is A Definite Risk Of Side Effects To The Breastfed Infants. However, Use Of The Drug In Breastfeeding Women Is Acceptable In Spite Of The Risk To The Infants, If The Drug Is Needed In A Life-threatening Situation Or For A Serious Disease For Which Safer Drugs Cannot Be Used Or Are Ineffective. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Prilocaine

No Studies Found