Medicine : Divalpro (125mg)

Name:Divalpro (125mg)
Type:Injection
Manufacturer:Zydus Cadila
Generic Use:Divalproex , Halobetasol
Composition:Divalproex(125 Mg) , Halobetasol(125mg)
Substitutes:divalpro (125mg) , divalpro (125mg)


Generic ( Divalproex )



Typical use Of Divalproex :Epilepsy, Migraine
Mechanism of action of Divalproex :Divalproex Sodium Dissociates To The Valproate Ion In The GI Tract And Increases Brain Concentrations Of GABA Which May Also Play An Important Role In The Prevention Of Migraine Attacks.
Drug Interaction of Divalproex : Divalproex Is Known To Interact With Other Drugs Like Mephenytoin. These Interactions Are Sometimes Beneficial And Sometimes May Pose Threats To Life. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Divalproex :Thrombocytopenia, Leucopenia, Bone Marrow Depression, Headache, Weight Gain, Edema.

INTERACTIONS OF DIVALPROEX


How Divalproex will impact on Pregnancy ?

Experiences Of Drug Use And Evidence From Studies In Pregnant Women Have Shown Risk To Fetus. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Divalproex will impact during lactation(breastfeeding) ?

Possibly Unsafe: Evidence From Studies In Breastfeeding Women Show That There Is A Definite Risk Of Side Effects To The Breastfed Infants. However, Use Of The Drug In Breastfeeding Women Is Acceptable In Spite Of The Risk To The Infants, If The Drug Is Needed In A Life-threatening Situation Or For A Serious Disease For Which Safer Drugs Cannot Be Used Or Are Ineffective. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Divalproex

No Studies Found






Generic ( Halobetasol )



Typical use Of Halobetasol :Used For The Relief Of The Inflammatory And Pruritic Manifestations.
Mechanism of action of Halobetasol :Halobetasol Propionate Is Thought To Act By The Induction Of Phospholipase A2 Inhibitory Proteins, Collectively Called Lipocortins. These Proteins Control The Biosynthesis Of Potent Mediators Of Inflammation Such As Prostaglandins And Leukotrienes By Inhibiting The Release Of Their Common Precursor Arachidonic Acid. Arachidonic Acid Is Released From Membrane Phospholipids By Phospholipase A2. The Initial Interaction, However, Is Due To The Drug Binding To The Cytosolic Glucocorticoid Receptor. After Binding The Receptor The Newly Formed Receptor-ligand Complex Translocates Itself Into The Cell Nucleus, Where It Binds To Many Glucocorticoid Response Elements (GRE) In The Promoter Region Of The Target Genes. The DNA Bound Receptor Then Interacts With Basic Transcription Factors, Causing The Increase In Expression Of Specific Target Genes.
Drug Interaction of Halobetasol :Used For The Relief Of The Inflammatory And Pruritic Manifestations.
Side effects of Halobetasol :Pustulation, Erythema, Skin Atrophy, Leukoderma, Acne, Itching, Secondary Infection, Telangiectasia, Urticaria, Dry Skin, Miliaria, Paresthesia, And Rash.

INTERACTIONS OF HALOBETASOL


How Halobetasol will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Halobetasol will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Halobetasol

No Studies Found