Generic ( Dextromethorphan Hydrobromide )
|Typical use Of Dextromethorphan Hydrobromide :||Cough Suppressant|
|Mechanism of action of Dextromethorphan Hydrobromide :||Dextromethorphan Is An Opioid-like Drug That Binds To And Acts As Antagonist To The NMDA Glutamatergic Receptor, It Is An Agonist To The Opioid Sigma 1 And Sigma 2 Receptors, It Is Also An Alpha3/beta4 Nicotinic Receptor Antagonist And Targets The Serotonin Reuptake Pump. Dextromethorphan Is Rapidly Absorbed From The Gastrointestinal Tract, Where It Enters The Bloodstream And Crosses The Blood-brain Barrier. The First-pass Through The Hepatic Portal Vein Results In Some Of The Drug Being Metabolized Into An Active Metabolite Of Dextromethorphan, Dextrorphan, The 3-hydroxy Derivative Of Dextromethorphan.|
|Drug Interaction of Dextromethorphan Hydrobromide :||None Mentioned.|
|Side effects of Dextromethorphan Hydrobromide :||Dizziness, GI Disturbances.|
INTERACTIONS OF DEXTROMETHORPHAN HYDROBROMIDE
How Dextromethorphan Hydrobromide will impact on Pregnancy ?Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.
How Dextromethorphan Hydrobromide will impact during lactation(breastfeeding) ?Possibly Unsafe: Evidence From Studies In Breastfeeding Women Show That There Is A Definite Risk Of Side Effects To The Breastfed Infants. However, Use Of The Drug In Breastfeeding Women Is Acceptable In Spite Of The Risk To The Infants, If The Drug Is Needed In A Life-threatening Situation Or For A Serious Disease For Which Safer Drugs Cannot Be Used Or Are Ineffective. Patients Should Follow The Advice Of The Doctor Regarding Its Use.
Medicine & Alcohol use and effect of Dextromethorphan HydrobromideNo Studies Found