D F O Nano Gel(30gm) Cream | Side effects | Usages

Medicine : D F O Nano Gel(30gm)

Name:	D F O Nano Gel(30gm)
Type:	Cream
Manufacturer:	Ozone Pharmaceuticals Ltd
Generic Use:	Diclofenac , Menthol , Methyl Salicylate , Linseed Oil
Composition:	Diclofenac(1.16%) , Menthol(5%) , Methyl Salicylate(10%) , Linseed Oil(3%)
Substitutes:	intagesic spray(50gm) , d f o nano gel(30gm) , intagesic spray(50gm) , d f o nano gel(30gm) , intagesic spray(50gm) , d f o nano gel(30gm) , intagesic spray(50gm) , d f o nano gel(30gm)

Generic ( Diclofenac )

Typical use Of Diclofenac :	Diclofenac Is Used In The Treatment Of Painful Conditions Affecting The Joints And Muscles Such As Degenerative Joint Diseases (osteoarthritis), Autoimmune Diseases Of Joints (rheumatoid Arthritis, Ankylosing Spondylitis) Lower Back Pain, Sprains Or Bone Fractures, Inflammation In And Around Joints (frozen Shoulder), Tendon Inflammation, Tendon Sheath Swelling, Pain And Inflammation Associated With Diseases Such As Gout, Pain And Swelling Following Skeletal Muscle, Dental And Other Minor Surgery.
Mechanism of action of Diclofenac :	Diclofenac Works By Blocking The Effect Of Chemicals Called Cyclooxygenase Enzymes. These Enzymes Help To Make Other Chemicals In The Body, Called Prostaglandins. Prostaglandins Are Produced At Sites Of Injury Or Damage, And Cause Pain And Swelling. By Blocking The Effect Of Cyclooxygenase Enzymes, Production Of Prostaglandins Are Reduced, Thus, Pain And Swelling Are Eased.
Drug Interaction of Diclofenac :	Diclofenac Should Be Avoided In Combination With Lithium, Blood Thinning Agents Such As Warfarin, Cyclosporine, Mifepristone, Methotrexate, Selective Serotonin Reuptake Inhibitors, Other Pain Killers, Corticosteroids, Diuretics, Tacrolimus, Zidovudine, And Quinolone Antibiotic Drugs. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Diclofenac :	Ulcers In The Stomach And Intestine, Urge To Vomit, Vomiting, Excessive Passage Of Wind, Constipation, Indigestion, Abdominal Pain, Bloody Or Black Tar Like Stools, Vomiting Blood Or Dark Coffee Ground Like Material, Moth Ulcers, Severe Allergic Reactions, Water Retention And Swelling, Rise In Blood Pressure, Heart Failure, Damage To The Kidneys, Elevation Of Liver Enzymes, Inflammation Of Liver, Jaundice, Visual Disturbances, Ringing/buzzing In Ears, Headache, Other Nervous System Disorders, Decrease In The Blood Cells.

INTERACTIONS OF DICLOFENAC

How Diclofenac will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Diclofenac will impact during lactation(breastfeeding) ?

Possibly Unsafe: Evidence From Studies In Breastfeeding Women Show That There Is A Definite Risk Of Side Effects To The Breastfed Infants. However, Use Of The Drug In Breastfeeding Women Is Acceptable In Spite Of The Risk To The Infants, If The Drug Is Needed In A Life-threatening Situation Or For A Serious Disease For Which Safer Drugs Cannot Be Used Or Are Ineffective. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Diclofenac

No Studies Found

Generic ( Menthol )

Typical use Of Menthol :	Pharmaceutical Aid
Mechanism of action of Menthol :	Menthol Primarily Activates The Cold-sensitive TRPM8 Receptors In The Skin. Menthol, After Topical Application, Causes A Feeling Of Coolness Due To Stimulation Of 'cold' Receptors By Inhibiting Ca++ Currents Of Neuronal Membranes. It May Also Yield Analgesic Properties Via Kappa-opioid Receptor Agonism.
Drug Interaction of Menthol :	Menthol Is Known To Interact With Other Drugs Like Alcohol. These Interactions Are Sometimes Beneficial And Sometimes May Pose Threats To Life. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Menthol :	Nystagmus, Contact Dermatitis, Apnea. Menthol Produces Potentially Life-threatening Effects Which Include Coma. Overdosage Of Menthol Include Irregularities In Heart Rhythm. The Symtomatic Adverse Effects Produced By Menthol Such As Vertigo, Drowsiness, Ataxia, Abdominal Pain, Nausea And Vomiting.

INTERACTIONS OF MENTHOL

How Menthol will impact on Pregnancy ?

Experiences Of Drug Use And Evidence From Studies In Pregnant Women Have Shown Risk To Fetus. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Menthol will impact during lactation(breastfeeding) ?

Medicine & Alcohol use and effect of Menthol

No Studies Found

Generic ( Methyl Salicylate )

Typical use Of Methyl Salicylate :	Musculoskeletal Disorders, Peripheral Vascular Disease, Respiratory Tract Infections, Soft Tissue Disorders.
Mechanism of action of Methyl Salicylate :	Methyl Salicylate Is Considered A Non-selective COX Inhibitorthat Is, It Inhibits Two Isoforms Of Cyclooxygenase, COX-1 And COX-2. The Analgesic, Antipyretic, And Anti-inflammatory Activity Of NSAIDs Appears To Be Achieved Mainly Through Inhibition Of COX-2, Whereas Inhibition Of COX-1 Would Be Responsible For Unwanted Effects On Platelet Aggregation And The Gastrointestinal Tract. Methyl Salicylate Directly And Irreversibly Inhibits The Activity Of Both Types Of Cyclo-oxygenases (COX-1 And COX-2) To Decrease The Formation Of Precursors Of Prostaglandins And Thromboxanes From Arachidonic Acid. Salicylate May Competitively Inhibit Prostaglandin Formation. Salicylate's Antirheumatic (nonsteroidal Anti-inflammatory) Actions Are A Result Of Its Analgesic And Anti-inflammatory Mechanisms.
Drug Interaction of Methyl Salicylate :	Tell Your Doctor Of All Prescription And Nonprescription Medication You May Use. Do Not Start Or Stop Any Medicine Without Doctor Or Pharmacist Approval.
Side effects of Methyl Salicylate :	Irritative Skin Reactions, Skin Ulcers, Stinging Of Skin.

INTERACTIONS OF METHYL SALICYLATE

How Methyl Salicylate will impact on Pregnancy ?

How Methyl Salicylate will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Methyl Salicylate

No Studies Found

Generic ( Linseed Oil )

Typical use Of Linseed Oil :	Used To Reduce Cholesterol Levels, To Slow Prostate Cancer Growth Before Surgery, And Topically For Skin Irritation.
Mechanism of action of Linseed Oil :	Not Known.
Drug Interaction of Linseed Oil :	None Mentioned.
Side effects of Linseed Oil :	Difficulty Breathing, Closing Of Your Throat, Swelling Of Your Lips, Tongue, Or Face.

INTERACTIONS OF LINSEED OIL

How Linseed Oil will impact on Pregnancy ?

There Are No Studies Available Regarding Its Use During Pregnancy. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Linseed Oil will impact during lactation(breastfeeding) ?

There Are No Studies Available Regarding Its Use During Lactation. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Linseed Oil

No Studies Found